| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4367946 | Binding | Inhibition of recombinant His-tagged BRAF V600E mutant (unknown origin) (444-723 residues) expressed in Escherichia coli BL21(DE3)-RIL using MEKK97R as substrate assessed as reduction in phosphorylation incubated for 20 mins by immunoblot assay | Homo sapiens | 13 | ALA4364309 | assay format | Scientific Literature | |
| 2. | ALA4367947 | Functional | Antiproliferative activity at human A375 cells expressing BRAF V600E mutant assessed as reduction in cell viability incubated for 96 hrs by MTT assay | Homo sapiens | 13 | ALA4364309 | cell-based format | Scientific Literature | |
| 3. | ALA4367948 | Binding | Inhibition of BRAF (unknown origin) at 1 uM relative to control | Homo sapiens | 3 | ALA4364309 | single protein format | Scientific Literature | |
| 4. | ALA4367949 | Binding | Inhibition of CRAF (unknown origin) at 1 uM relative to control | Homo sapiens | 3 | ALA4364309 | single protein format | Scientific Literature |
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