| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4399580 | P | Lipophilicity, logD of compound | 5 | ALA4396928 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA4399581 | A | Permeability across apical to basolateral side in human Caco2 cells measured at 120 mins by LC-MS/MS analysis | Homo sapiens | 3 | ALA4396928 | cell-based format | Scientific Literature | |
| 3. | ALA4399584 | B | Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scintillation counter | Homo sapiens | 22 | ALA4396928 | assay format | Scientific Literature | |
| 4. | ALA4399585 | B | Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP by spectrophotometric analysis | Homo sapiens | 8 | ALA4396928 | single protein format | Scientific Literature | |
| 5. | ALA4399586 | B | Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ATP by spectrophotometric analysis | Homo sapiens | 8 | ALA4396928 | single protein format | Scientific Literature | |
| 6. | ALA4399589 | B | Inhibition of ROCK (unknown origin) using Myelin Basic Protein as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scintillation counter | Homo sapiens | 3 | ALA4396928 | protein format | Scientific Literature | |
| 7. | ALA4399592 | B | Inhibition of JAK2 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scintillation counter | Homo sapiens | 3 | ALA4396928 | single protein format | Scientific Literature | |
| 8. | ALA4399593 | A | Unbound hepatic clearance in rat hepatocytes assessed per million cells | Rattus norvegicus | 3 | ALA4396928 | cell-based format | Scientific Literature | |
| 9. | ALA4399594 | A | Unbound hepatic clearance in human hepatocytes assessed per million cells | Homo sapiens | 3 | ALA4396928 | cell-based format | Scientific Literature | |
| 10. | ALA4399595 | A | Clearance in iv dosed rat | Rattus norvegicus | 5 | ALA4396928 | organism-based format | Scientific Literature | |
| 11. | ALA4399596 | A | Half-life in iv dosed rat | Rattus norvegicus | 5 | ALA4396928 | organism-based format | Scientific Literature | |
| 12. | ALA4399597 | A | Volume of distribution at steady state in iv dosed rat | Rattus norvegicus | 4 | ALA4396928 | organism-based format | Scientific Literature | |
| 13. | ALA4399601 | A | Efflux ratio of permeability in human Caco2 cells by LC-MS/MS analysis | Homo sapiens | 3 | ALA4396928 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!