| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4384228 | Functional | Antiparasitic activity against Giardia lamblia WB trophozoites after 24 to 48 hrs by CellTiter-Glo luminescent cell viability assay | Giardia intestinalis | 67 | ALA4382237 | organism-based format | Scientific Literature | |
| 2. | ALA4384229 | Functional | Antiparasitic activity against Entamoeba histolytica HM-1:IMSS trophozoites after 24 to 48 hrs by CellTiter-Glo luminescent cell viability assay | Entamoeba histolytica | 50 | ALA4382237 | organism-based format | Scientific Literature | |
| 3. | ALA4384231 | Functional | Antibacterial activity against Mycobacterium tuberculosis H37Rv after 5 days under normoxic condition by resazurin dye-based fluorescence assay | Mycobacterium tuberculosis | 66 | ALA4382237 | organism-based format | Scientific Literature | |
| 4. | ALA4384233 | Functional | Antibacterial activity against non-replicating Mycobacterium tuberculosis H37Rv after 5 days under hypoxic condition by resazurin dye-based fluorescence assay | Mycobacterium tuberculosis | 64 | ALA4382237 | organism-based format | Scientific Literature | |
| 5. | ALA4384236 | Functional | Antiparasitic activity against bloodstream form of Trypanosoma brucei brucei strain 427 after 48 hrs by resazurin dye-based assay | Trypanosoma brucei brucei | 48 | ALA4382237 | organism-based format | Scientific Literature | |
| 6. | ALA4384259 | Physicochemical | Kinetic solubility of compound in water at 200 uM after 24 hrs by LC-UV analysis | 7 | ALA4382237 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4384260 | Physicochemical | Kinetic solubility of compound in pH 7.4 PBS at 200 uM after 24 hrs by LC-UV analysis | 7 | ALA4382237 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA5106641 | Physicochemical | Solubility of compound in water by LC-UV analysis | 8 | ALA5104178 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA5106642 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as bacterial growth inhibition incubated for 5 days under normoxic condition by resazurin microtiter assay | Mycobacterium tuberculosis | 19 | ALA5104178 | organism-based format | Scientific Literature | |
| 10. | ALA5106643 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis H37Ra ATCC 25177 assessed as bacterial growth inhibition incubated for 6 days under normoxic condition by resazurin microtiter assay | Mycobacterium tuberculosis | 11 | ALA5104178 | organism-based format | Scientific Literature | |
| 11. | ALA5106644 | Functional | Antimycobacterial activity against Mycobacterium avium ATCC 25291 assessed as bacterial growth inhibition incubated for 6 days under normoxic condition by resazurin microtiter assay | Mycobacterium avium | 11 | ALA5104178 | organism-based format | Scientific Literature | |
| 12. | ALA5106645 | Functional | Antimycobacterial activity against Mycobacterium smegmatis mc2155 ATCC 700084 assessed as bacterial growth inhibition incubated for 24 hrs under normoxic condition by resazurin microtiter assay | Mycolicibacterium smegmatis | 11 | ALA5104178 | organism-based format | Scientific Literature | |
| 13. | ALA5106646 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as bacterial growth inhibition incubated for 5 days under hypoxic condition by resazurin microtiter assay | Mycobacterium tuberculosis | 16 | ALA5104178 | organism-based format | Scientific Literature | |
| 14. | ALA5106648 | Binding | Substrate activity at Mycobacterium tuberculosis Ddn expressed in Escherichia coli BL21 (DE3) assessed as oxidation of F420H2 by measuring Kcat by spectrophotometric analysis | Mycobacterium tuberculosis | 15 | ALA5104178 | assay format | Scientific Literature | |
| 15. | ALA5106649 | Binding | Substrate activity at Mycobacterium tuberculosis Ddn expressed in Escherichia coli BL21 (DE3) assessed as oxidation of F420H2 by measuring Km by spectrophotometric analysis | Mycobacterium tuberculosis | 15 | ALA5104178 | assay format | Scientific Literature | |
| 16. | ALA5106650 | Binding | Substrate activity at Mycobacterium tuberculosis Ddn expressed in Escherichia coli BL21 (DE3) assessed as oxidation of F420H2 by measuring Kcat/Km by spectrophotometric analysis | Mycobacterium tuberculosis | 15 | ALA5104178 | assay format | Scientific Literature | |
| 17. | ALA5106653 | ADME | Plasma protein binding in human | Homo sapiens | 6 | ALA5104178 | cell-free format | Scientific Literature | |
| 18. | ALA5106654 | ADME | Plasma protein binding in mouse | Mus musculus | 6 | ALA5104178 | cell-free format | Scientific Literature | |
| 19. | ALA5106655 | ADME | Metabolic stability in human microsomes assessed as compound remaining measured after 2 hrs | Homo sapiens | 5 | ALA5104178 | microsome format | Scientific Literature | |
| 20. | ALA5106656 | ADME | Metabolic stability in mouse microsomes assessed as compound remaining measured after 2 hrs | Mus musculus | 5 | ALA5104178 | microsome format | Scientific Literature |
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