# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4390078 | Binding | Positive allosteric modulation activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel current at -90 mV holding potential preincubated for 2 mins followed by co-application with acetylcholine for 10 secs by two-electrode voltage clamp method | Homo sapiens | 32 | ALA4387746 | cell-based format | Scientific Literature | |
2. | ALA4390079 | Binding | Positive allosteric modulation activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel current at 10 uM at -90 mV holding potential preincubated for 2 mins followed by co-application with acetylcholine for 10 secs by two-electrode voltage clamp method relative to control | Homo sapiens | 32 | ALA4387746 | cell-based format | Scientific Literature | |
3. | ALA4390086 | Binding | Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel current at -90 mV holding potential by two-electrode voltage clamp method | Homo sapiens | 32 | ALA4387746 | cell-based format | Scientific Literature |