# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
2. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
3. | ALA4513083 | Functional | Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 147 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
4. | ALA4513084 | Toxicity | Toxicity CC50 against VERO-E6 cells determined at 48 hours by high content imaging (same conditions as 2_LEY without exposure to 0.01 MOI SARS CoV-2 virus) | Chlorocebus sabaeus | 147 | ALA4495565 | cell-based format | SARS-CoV-2 Screening Data 2020-21 | |
5. | ALA4513085 | Toxicity | Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells versus toxicity against VERO-E6 cells (CC50/IC50) | Chlorocebus sabaeus | 147 | ALA4495565 | cell-based format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA5151350 | Binding | Inhibition of SIK1 (unknown origin) | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
7. | ALA5151351 | Binding | Inhibition of SIK2 (unknown origin) | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
8. | ALA5151352 | Binding | Inhibition of SIK3 (unknown origin) | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
9. | ALA5151353 | Binding | Inhibition of JAK2 (unknown origin) at 0.5 uM | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
10. | ALA5151354 | Binding | Inhibition of LCK (unknown origin) at 0.5 uM | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
11. | ALA5151355 | Binding | Inhibition of NUAK2 (unknown origin) at 0.5 uM | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
12. | ALA5151356 | Binding | Inhibition of VGFR2 (unknown origin) at 0.5 uM | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
13. | ALA5151357 | Binding | Inhibition of SRPK1 (unknown origin) at 0.5 uM | Homo sapiens | 1 | ALA5149988 | single protein format | Scientific Literature | |
14. | ALA5303712 | Functional | Inhibition of SARS-CoV-2-induced cytopathy was measured 4 days after infection of EGFP-labeled Green monkey Vero cells by fluorescence imaging. | Chlorocebus sabaeus | 134 | ALA5303708 | organism-based format | EU-OPENSCREEN dataset | |
15. | ALA5303715 | Toxicity | Cytotoxicity activity against human HepG2 cells assessed by CellTiter-Glo luminescent cell viability assay. | Homo sapiens | 1,545 | ALA5303711 | cell-based format | EU-OPENSCREEN dataset |