| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4362834 | Binding | Agonist activity at APC-labeled biotinylated RORgammaT LBD (unknown origin) assessed as induction of biotinylated SRC-1 peptide recruitment incubated for 1 hr by dual FRET assay | Homo sapiens | 41 | ALA4359888 | single protein format | Scientific Literature | |
| 2. | ALA4362835 | Binding | Agonist activity at APC-labeled biotinylated RORgammaT LBD (unknown origin) assessed as induction of biotinylated SRC-1 peptide recruitment incubated for 1 hr by dual FRET assay relative to control | Homo sapiens | 41 | ALA4359888 | single protein format | Scientific Literature | |
| 3. | ALA4362836 | ADME | Metabolic stability in mouse liver microsomes assessed as half life of compound at 1 uM and measured for 60 mins in presence of NADPH by HPLC-MS/MS analysis | Mus musculus | 31 | ALA4359888 | microsome format | Scientific Literature | |
| 4. | ALA4362837 | Binding | Transactivation of human GAL4-fused RORgammaT LBD expressed in human HEK293T cells incubated for 16 to 20 hrs by steady-glo luciferase assay | Homo sapiens | 26 | ALA4359888 | cell-based format | Scientific Literature | |
| 5. | ALA4362838 | Binding | Transactivation of human GAL4-fused RORgammaT LBD expressed in human HEK293T cells incubated for 16 to 20 hrs by steady-glo luciferase assay relative to control | Homo sapiens | 26 | ALA4359888 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!