| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4362207 | B | Inhibition of N-terminal GST-tagged human VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using FAM-22 peptide as substrate incubated for 10 mins followed by substrate addition by caliper method | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 2. | ALA4362208 | B | Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using FAM-22 peptide as substrate incubated for 10 mins followed by substrate addition by caliper method | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 3. | ALA4362210 | A | Cytotoxicity against human A549 cells assessed as inhibition of cell growth at 0.5 uM after 48 hrs under normoxic condition by CCk-8 assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4362211 | A | Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth at 0.5 uM after 48 hrs under normoxic condition by CCk-8 assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA4362212 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth at 0.5 uM after 48 hrs under hypoxic condition (200 uM CoCl2) by CCk-8 assay relative to control (Rvb = 59.94%) | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4362213 | F | Antiproliferative activity against human NCI-H446 cells assessed as inhibition of cell growth at 0.5 uM after 48 hrs under hypoxic condition (200 uM CoCl2) by CCk-8 assay relative to control (Rvb = 65.84%) | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4362214 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth at 0.5 uM in hypoxia condition (200 uM CoCl2) and under irradiation at 8 Gy for 24 hrs and measured after 24 hrs by CCK8 assay (Rvb = 64.135%) | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4362215 | F | Antiproliferative activity against human NCI-H446 cells assessed as inhibition of cell growth at 0.5 uM in hypoxia condition (200 uM CoCl2) and under irradiation at 8 Gy for 24 hrs and measured after 24 hrs by CCK8 assay (Rvb = 68.77%) | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA4362216 | F | Antiproliferative activity against human A549 cells assessed as hypoxic sensitive enhancement ratio in presence of CoCl2 | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA4362217 | F | Antiproliferative activity against human A549 cells assessed as hypoxic sensitive enhancement ratio in presence of Cocl2 under irradiation | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA4362231 | F | Antiproliferative activity against human NCI-H446 cells assessed as hypoxic sensitive enhancement ratio in presence of CoCl2 | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA4362232 | F | Antiproliferative activity against human NCI-H446 cells assessed as hypoxic sensitive enhancement ratio in presence of Cocl2 under irradiation | Homo sapiens | 8 | cell-based format | Scientific Literature |
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