| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4423275 | B | Inhibition of ABCG2 (unknown origin) expressed in MDCK II BCRP cells assessed as effect on pheophorbide A accumulation after 120 mins by flow cytometric analysis | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
| 2. | ALA4423276 | B | Inhibition of ABCG2 (unknown origin) expressed in MDCK II BCRP cells assessed as effect on heophorbide A accumulation at 5 to 10 uM after 120 mins by flow cytometric analysis relative to control | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
| 3. | ALA4423277 | B | Inhibition of ABCB1 in human A2780/ADR cells preincubated for 30 mins followed by calcein AM addition and measured every 60 secs for 1 hr by fluorescence assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA4423279 | B | Inhibition of ABCB1 in human A2780/ADR cells assessed as potentiation of daunorubicin-induced cytotoxicity measured after 72 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 5. | ALA4423280 | B | Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells co-expressing BCRP (unknown origin) assessed as potentiation of SN-38-induced cytotoxicity measured after 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4423281 | A | Growth inhibition of human A2780 cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA4423282 | A | Growth inhibition of human A2780/ADR cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 8. | ALA4423283 | A | Growth inhibition of MDCK2 cells after 72 hrs by MTT assay | Canis lupus familiaris | 11 | cell-based format | Scientific Literature | ||
| 9. | ALA4423284 | A | Growth inhibition of MDCK2 cells expressing BCRP (unknown origin) after 72 hrs by MTT assay | Canis lupus familiaris | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA4423285 | T | Therapeutic index, ratio of GI50 for human A2780/ADR cells to EC50 for ABCB1 in human A2780/ADR cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 11. | ALA4423286 | T | Therapeutic index, ratio of GI50 for MDCK2 cells expressing BCRP (unknown origin) to EC50 for ABCG2 (unknown origin) co-expressed in MDCK2 cells expressing BCRP (unknown origin) | 11 | cell-based format | Scientific Literature |
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