# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4347588 | Functional | Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4346670 | cell-based format | Scientific Literature | |
2. | ALA4347589 | Functional | Antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4346670 | cell-based format | Scientific Literature | |
3. | ALA4347596 | Binding | Inhibition of recombinant human JAK2 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assay | Homo sapiens | 27 | ALA4346670 | single protein format | Scientific Literature | |
4. | ALA4347598 | Binding | Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 27 | ALA4346670 | cell-based format | Scientific Literature | |
5. | ALA4347604 | Binding | Inhibition of HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 8 | ALA4346670 | single protein format | Scientific Literature | |
6. | ALA4347605 | Binding | Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 8 | ALA4346670 | single protein format | Scientific Literature | |
7. | ALA4347606 | Binding | Inhibition of HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 8 | ALA4346670 | single protein format | Scientific Literature | |
8. | ALA4347612 | Functional | Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4346670 | cell-based format | Scientific Literature | |
9. | ALA4347613 | Functional | Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4346670 | cell-based format | Scientific Literature |