# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4349421 | Binding | Protac activity against VHL/androgen receptor in human VCaP cells assessed as induction of androgen receptor protein degradation by Western blot analysis | Homo sapiens | 1 | ALA4346721 | cell-based format | Scientific Literature | |
2. | ALA4349422 | Binding | Protac activity against VHL/androgen receptor in human VCaP cells assessed as induction of androgen receptor protein degradation by Western blot analysis relative to control | Homo sapiens | 1 | ALA4346721 | cell-based format | Scientific Literature | |
3. | ALA4618788 | Binding | Protac activity at E3 ubiquitin-protein ligase/AR in human LNCAP cells assessed as induction of AR degradation after 24 hrs by ELISA relative to control | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
4. | ALA4618789 | Binding | Protac activity at E3 ubiquitin-protein ligase/AR in human LNCAP cells assessed as induction of AR degradation after 24 hrs by ELISA | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
5. | ALA4618790 | Binding | Protac activity at E3 ubiquitin-protein ligase/AR in human VCAP cells assessed as induction of AR degradation after 24 hrs by ELISA relative to control | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
6. | ALA4618791 | Binding | Protac activity at E3 ubiquitin-protein ligase/AR in human VCAP cells assessed as induction of AR degradation after 24 hrs by ELISA | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
7. | ALA4618792 | Binding | Protac activity at E3-ubiquitin ligase/AR in human LNCAP cells assessed as AR degradation up to 15 mins by ELISA relative to control | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
8. | ALA4618793 | Binding | Protac activity at E3-ubiquitin ligase/AR in human VCaP cells assessed as AR degradation up to 15 mins by ELISA relative to control | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
9. | ALA4618794 | Binding | Protac activity at E3-ubiquitin ligase/AR in human LNCAP cells assessed as time taken for maximum degradation by ELISA | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
10. | ALA4618795 | Binding | Protac activity at E3-ubiquitin ligase/AR in human VCaP cells assessed as time taken for maximal degradation by ELISA | Homo sapiens | 8 | ALA4616689 | cell-based format | Scientific Literature | |
11. | ALA5137682 | Binding | Protac activity at VHL/androgen receptor in resistant human LNCaP cells assessed as fold reduction of AR levels at 10 uM | Homo sapiens | 2 | ALA5136974 | cell-based format | Scientific Literature |