# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4415068 | Binding | Inhibition of NS4B in Dengue virus 2 NGC infected in human HuH7 replicon cells lysates at 10 ujM incubated for 48 hrs by SDS-PAGE based pull down assay | dengue virus type 2 | 2 | ALA4414551 | subcellular format | Scientific Literature | |
2. | ALA4415069 | Functional | Antiviral activity against Dengue virus 4 D4MY01-22713 infected in human HuH7 replicon cells expressing Renilla luciferase and neomycin-resistance genes assessed as reduction in viral replication up to 10 uM incubated for 48 hrs by luciferase reporter replicon-based assay | dengue virus type 4 | 1 | ALA4414551 | organism-based format | Scientific Literature | |
3. | ALA4415070 | Functional | Antiviral activity against Dengue virus 1 WestPac infected in human HuH7 replicon cells expressing Renilla luciferase and neomycin-resistance genes assessed as reduction in viral replication up to 10 uM incubated for 48 hrs by luciferase reporter replicon-based assay | dengue virus type 1 | 1 | ALA4414551 | organism-based format | Scientific Literature | |
4. | ALA4415071 | ADME | Cytotoxicity in human HuH7 replicon cells infected with Dengue virus 2 NGC assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-Glo reagent based assay | Homo sapiens | 63 | ALA4414551 | cell-based format | Scientific Literature | |
5. | ALA4415073 | Functional | Antiviral activity against Dengue virus 3 D3MY05-34640 infected in human HuH7 replicon cells expressing Renilla luciferase and neomycin-resistance genes assessed as reduction in viral replication incubated for 48 hrs by luciferase reporter replicon-based assay | dengue virus type 3 | 60 | ALA4414551 | organism-based format | Scientific Literature | |
6. | ALA4415074 | Functional | Antiviral activity against Dengue virus 2 NGC infected in human HuH7 replicon cells expressing Renilla luciferase and neomycin-resistance genes assessed as reduction in viral replication incubated for 48 hrs by luciferase reporter replicon-based assay | dengue virus type 2 | 63 | ALA4414551 | organism-based format | Scientific Literature |