#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4349912	Binding	Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by TR-FRET assay	Homo sapiens	46	ALA4346735	single protein format	Scientific Literature
2.	ALA4349913	Binding	Transactivation of recombinant GAL4-DBD fused RORgammat LBD (unknown origin) expressed in HEK293T cells incubated for 18 to 24 hrs by dual-Glo luciferase assay	Homo sapiens	44	ALA4346735	cell-based format	Scientific Literature
3.	ALA4349914	ADME	Drug metabolism in mouse liver microsomes assessed as oxidation metabolic rate at 1 uM preincubated for 5 mins followed by NADPH addition after 30 mins by LC-MS/MS analysis	Mus musculus	3	ALA4346735	microsome format	Scientific Literature
4.	ALA4349915	ADME	Drug metabolism in rat liver microsomes assessed as oxidation metabolic rate at 1 uM preincubated for 5 mins followed by NADPH addition after 30 mins by LC-MS/MS analysis	Rattus norvegicus	3	ALA4346735	microsome format	Scientific Literature
5.	ALA4349916	ADME	Drug metabolism in human pooled liver microsomes assessed as oxidation metabolic rate at 1 uM preincubated for 5 mins followed by NADPH addition after 30 mins by LC-MS/MS analysis	Homo sapiens	3	ALA4346735	microsome format	Scientific Literature
6.	ALA4349917	ADME	AUC (0 to t) in Balb/c mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	3	ALA4346735	organism-based format	Scientific Literature
7.	ALA4349918	ADME	Clearance in Balb/c mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	3	ALA4346735	organism-based format	Scientific Literature
8.	ALA4349919	ADME	Half life in Balb/c mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	3	ALA4346735	organism-based format	Scientific Literature
9.	ALA4349920	ADME	Oral bioavailability in Balb/c mouse at 10 mg/kg administered via gavage by LC-MS/MS analysis	Mus musculus	3	ALA4346735	organism-based format	Scientific Literature
10.	ALA4349936	Binding	Inverse agonist activity at RORgammat in mouse splenocytes derived naive T cells assessed as suppression of T cell differentiation to Th17 cells by measuring IL-17 secretion in presence of anti-CD4/anti-IFNgamma/TGFbeta/IL-6 for 6 days by ELISA	Mus musculus	4	ALA4346735	cell-based format	Scientific Literature
11.	ALA4349942	ADME	Metabolic stability in rat hepatocytes assessed as parent compound remaining after 30 mins	Rattus norvegicus	1	ALA4346735	cell-based format	Scientific Literature