# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4430645 | Binding | Inhibition of full length recombinant human HDAC2 expressed in baculovirus expression system using fluorogenic peptide RHKK(Ac) as substrate by fluorescence assay | Homo sapiens | 43 | ALA4428107 | assay format | Scientific Literature | |
2. | ALA4430646 | Functional | Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay | Homo sapiens | 43 | ALA4428107 | cell-based format | Scientific Literature | |
3. | ALA4430647 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay | Homo sapiens | 43 | ALA4428107 | cell-based format | Scientific Literature | |
4. | ALA4430648 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay | Homo sapiens | 43 | ALA4428107 | cell-based format | Scientific Literature | |
5. | ALA4430649 | Functional | Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability after 70 hrs by Quanti-blue assay | Homo sapiens | 42 | ALA4428107 | cell-based format | Scientific Literature | |
6. | ALA4430650 | Functional | Antiproliferative activity against human HUT78 cells assessed as reduction in cell viability after 70 hrs by Quanti-blue assay | Homo sapiens | 42 | ALA4428107 | cell-based format | Scientific Literature | |
7. | ALA4430651 | ADME | Antiproliferative activity against human PBMC assessed as reduction in cell viability after 70 hrs by Quanti-blue assay | Homo sapiens | 42 | ALA4428107 | cell-based format | Scientific Literature | |
8. | ALA4430654 | Functional | Immunomodulatory activity in human TALL-104 cells assessed as effect on degranulation by measuring augmentation of CD3-stimulated anti-LAMP fluorescence at 100 uM preincubated for 30 mins followed by anti-LAMP addition and incubated for 50 mins in the dark by flow cytometric analysis relative to control | Homo sapiens | 42 | ALA4428107 | cell-based format | Scientific Literature |