# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4430710 | B | Inhibition of biotinylated VEGF-A165 binding to recombinant NRP1 (unknown origin) at 100 uM measured after 2 hrs by competition binding assay relative to VEGF-A165 | Homo sapiens | 15 | single protein format | Scientific Literature | ||
2. | ALA4430711 | B | Inhibition of biotinylated VEGF-A165 binding to recombinant NRP1 (unknown origin) measured after 2 hrs by competition binding assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
3. | ALA4430712 | B | Inhibition of biotinylated VEGF-A165 binding to recombinant KDR (unknown origin) at 100 uM measured after 2 hrs by competition binding assay relative to VEGF-A165 | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA4430713 | B | Inhibition of biotinylated VEGF-A165 binding to recombinant KDR (unknown origin) measured after 2 hrs by competition binding assay relative to VEGF-A165 | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA4430714 | B | Selectivity ratio of IC50 for recombinant KDR (unknown origin) to IC50 for recombinant NRP1 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA4430715 | B | Binding affinity to NRP1 in HUVEC assessed as decrease in ERK phosphorylation at 50 uM by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4430716 | B | Binding affinity to NRP1 in HUVEC assessed as increase in AKT phosphorylation at 50 uM by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA4430717 | A | Cytotoxicity against HUVEC at 12.5 to 200 uM by WST assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4430719 | F | Antiangiogenic activity in HUVEC assessed as inhibition of tubule like capillary formation at 50 uM measured after overnight incubation by matrigel assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA4430720 | A | Proinvasive activity in HUVEC at 50 uM measured after 24 hrs by matrigel assay | Homo sapiens | 4 | cell-based format | Scientific Literature |