#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4406959	Functional	Anti-necroptotic activity in human HT-29 cells assessed as inhibition of NFalpha/SM-164/Z-VAD-fmk-induced necroptosis measured after 12 hrs by celltiter-glo luminescent cell viability assay	Homo sapiens	37	ALA4406794	cell-based format	Scientific Literature
2.	ALA4406960	ADME	Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PCR based KINOMEscan assay	Homo sapiens	28	ALA4406794	assay format	Scientific Literature
3.	ALA4406961	Binding	Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PCR based KINOMEscan assay	Homo sapiens	28	ALA4406794	assay format	Scientific Literature
4.	ALA4406963	ADME	Cytotoxicity against human HT-29 cells measured after 12 hrs by CellTiter-Glo Luminescent assay	Homo sapiens	28	ALA4406794	cell-based format	Scientific Literature
5.	ALA4406998	Functional	Protection against TNFalpha/Z-VAD-fmk-induced C57BL/6J mouse model of systemic inflammatory response syndrome assessed as increase in body temperature at 5 to 50 mg/kg, po administered via gavage 2 hrs prior to Z-VAD-fmk addition for 15 mins followed by TNFalpha stimulation for 1 hr and subsequent Z-VAD-fmk addition meaured up to 50 hrs post TNFalpha stimulation by electric thermometer	Mus musculus	3	ALA4406794	organism-based format	Scientific Literature
6.	ALA4406999	Functional	Protection against TNFalpha/Z-VAD-fmk-induced C57BL/6J mouse model of systemic inflammatory response syndrome assessed as increase in mouse survial at 5 to 50 mg/kg, po administered via gavage 2 hrs prior to Z-VAD-fmk addition for 15 mins followed by TNFalpha stimulation for 1 hr and subsequent Z-VAD-fmk addition meaured up to 50 hrs post TNFalpha stimulation	Mus musculus	3	ALA4406794	organism-based format	Scientific Literature
7.	ALA4822732	Functional	Anti-necroptotic activity in human HT-29 cells assessed as inhibition of TNFalpha/Z-VAD-fmk (TCZ)-induced necroptosis pretreated for 8 to 12 hrs	Homo sapiens	5	ALA4819126	cell-based format	Scientific Literature
8.	ALA4822733	Binding	Inhibition of human wild type RIPK1 (M1 to K305) expressed in bacterial system by kinomescan assay	Homo sapiens	5	ALA4819126	assay format	Scientific Literature
9.	ALA4822734	Binding	Inhibition of human wild type RIPK3 (M1 to Q307) expressed in bacterial system by kinomescan assay	Homo sapiens	5	ALA4819126	assay format	Scientific Literature
10.	ALA5152911	Binding	Binding affinity to RIPK1 (unknown origin) by Kinomescan method	Homo sapiens	6	ALA5150038	single protein format	Scientific Literature
11.	ALA5152912	Binding	Binding affinity to RIPK3 (unknown origin) by Kinomescan method	Homo sapiens	5	ALA5150038	single protein format	Scientific Literature
12.	ALA5152942	Functional	Anti-necrotic activity in human HT-29 cells incubated for 0.5 hrs in presence of TCZ/Z-VAD-FMK/hTNF-alpha by celltiter-glo luminescent cell viability assay	Homo sapiens	3	ALA5150038	cell-based format	Scientific Literature