# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4424210 | B | Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed by enzyme addition | Homo sapiens | 3 | ALA4422658 | assay format | Scientific Literature | |
2. | ALA4424211 | B | Inhibition of recombinant human N-terminal GST-tagged TCPTP catalytic domain (2 to 315 residues) expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed by enzyme addition | Homo sapiens | 3 | ALA4422658 | assay format | Scientific Literature | |
3. | ALA4424212 | B | Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed by enzyme addition | Homo sapiens | 3 | ALA4422658 | assay format | Scientific Literature | |
4. | ALA4424213 | B | Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed by enzyme addition | Homo sapiens | 3 | ALA4422658 | assay format | Scientific Literature | |
5. | ALA4424214 | B | Inhibition of recombinant human SHP2 expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed by enzyme addition | Homo sapiens | 3 | ALA4422658 | assay format | Scientific Literature | |
6. | ALA4424215 | B | Selectivity ratio of IC50 for recombinant human N-terminal GST-tagged TCPTP catalytic domain (2 to 315 residues) expressed in Escherichia coli to IC50 for recombinant human PTP1B expressed in Escherichia coli | Homo sapiens | 2 | ALA4422658 | assay format | Scientific Literature | |
7. | ALA4424216 | B | Selectivity ratio of IC50 for recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli to IC50 for recombinant human PTP1B expressed in Escherichia coli | Homo sapiens | 1 | ALA4422658 | assay format | Scientific Literature | |
8. | ALA4424217 | B | Selectivity ratio of IC50 for recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli to IC50 for recombinant human PTP1B expressed in Escherichia coli | Homo sapiens | 1 | ALA4422658 | assay format | Scientific Literature | |
9. | ALA4424218 | B | Selectivity ratio of IC50 for recombinant human SHP2 expressed in Escherichia coli to IC50 for recombinant human PTP1B expressed in Escherichia coli | Homo sapiens | 1 | ALA4422658 | assay format | Scientific Literature | |
10. | ALA4424219 | B | Competitive inhibition of recombinant human PTP1B expressed in Escherichia coli using varying levels of p-nitrophenol as substrate by Lineweaver-burk plot analysis | Homo sapiens | 2 | ALA4422658 | assay format | Scientific Literature |