#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4433277	B	Displacement of [3H]-N-alpha-methylhistamine from human recombinant full length H3R expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation counting method	Homo sapiens	14	ALA4433195	cell-based format	Scientific Literature
2.	ALA4433278	F	Antagonist activity at human H3R expressed in HEK293 cells assessed as reduction in R)(-)-alpha methylhistamine-induced inhibition of forskolin-induced cAMP accumulation by TR-FRET based LANCE ultra cAMP immunoassay	Homo sapiens	2	ALA4433195	cell-based format	Scientific Literature
3.	ALA4433279	F	Reversal of RAMH-induced dipsogenia in Wistar rat (Krf:(WI) WU) assessed as inhibition of RAMH-induced drinking response pretreated for 30 mins followed by RAMH stimulation for 20 mins and measured for 30 mins	Rattus norvegicus	2	ALA4433195	organism-based format	Scientific Literature
4.	ALA4433281	B	Displacement of [3H]histamine from human recombinant H4R expressed in CHO cells incubated for 60 mins by microbeta scintillation counter method	Homo sapiens	2	ALA4433195	cell-based format	Scientific Literature
5.	ALA4433282	B	Antagonist activity at histamine H1 receptor in guinea-pig ileum assessed as inhibition of histamine-induced contractions incubated for 15 mins	Cavia porcellus	3	ALA4433195	tissue-based format	Scientific Literature
6.	ALA4433283	B	Antagonist activity at muscarinic M3 receptor in guinea-pig ileum assessed as inhibition of carbachol-induced contractions incubated for 15 mins	Cavia porcellus	3	ALA4433195	tissue-based format	Scientific Literature
7.	ALA4433285	B	Inhibition of human ERG expressed in CHO cells at holding potential of -90 mV by patch clamp method	Homo sapiens	4	ALA4433195	cell-based format	Scientific Literature
8.	ALA4433286	B	Selectivity ratio of Ki for human H4R to Ki for human H3R	Homo sapiens	2	ALA4433195	assay format	Scientific Literature
9.	ALA4433287	A	Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by cellTiter 96 AQueous non-radioactive cell proliferation assay	Homo sapiens	3	ALA4433195	cell-based format	Scientific Literature
10.	ALA4433288	A	Ratio of test compound IC50 to doxorubicin IC50 for cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by cellTiter 96 AQueous non-radioactive cell proliferation assay	Homo sapiens	2	ALA4433195	cell-based format	Scientific Literature
11.	ALA4433289	T	Mutagenicity in Salmonella typhimurium TA98 assessed as fold increase in number of positive wells over the solvent control baseline upto 10 uM incuabted for 90 mins and measured after 48 hrs by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	2	ALA4433195	assay format	Scientific Literature
12.	ALA4433290	T	Mutagenicity in Salmonella typhimurium TA100 assessed as fold increase in number of positive wells over the solvent control baseline upto 10 uM incuabted for 90 mins and measured after 48 hrs by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	2	ALA4433195	assay format	Scientific Literature
13.	ALA4433293	A	Metabolic stability in human recombinant liver microsomes assessed as retention time at 50 uM preincubated for 5 mins followed by NADPH addition and measured after 120 mins by UPLC-MS analysis	Homo sapiens	6	ALA4433195	microsome format	Scientific Literature
14.	ALA4433295	A	Metabolic stability in human recombinant liver microsomes assessed as metabolite M formation at 50 uM preincubated for 5 mins followed by NADPH addition and measured after 120 mins by UPLC-MS analysis	Homo sapiens	2	ALA4433195	microsome format	Scientific Literature
15.	ALA4433296	A	Metabolic stability in human recombinant liver microsomes assessed as metabolite M1 formation at 50 uM preincubated for 5 mins followed by NADPH addition and measured after 120 mins by UPLC-MS analysis	Homo sapiens	2	ALA4433195	microsome format	Scientific Literature
16.	ALA4433297	A	Metabolic stability in human recombinant liver microsomes assessed as metabolite M2 formation at 50 uM preincubated for 5 mins followed by NADPH addition and measured after 120 mins by UPLC-MS analysis	Homo sapiens	2	ALA4433195	microsome format	Scientific Literature
17.	ALA4433298	A	Metabolic stability in human recombinant liver microsomes assessed as metabolite M3 formation at 50 uM preincubated for 5 mins followed by NADPH addition and measured after 120 mins by UPLC-MS analysis	Homo sapiens	2	ALA4433195	microsome format	Scientific Literature
18.	ALA4433304	A	Inhibition of human recombinant CYP3A4 using luciferin as substrate at 0.025 to 25 uM preincubated for 10 mins followed by substrate addition and measured after 50 mins in presence of NADPH by CYP450-Glo assay	Homo sapiens	2	ALA4433195	single protein format	Scientific Literature
19.	ALA4433305	A	Activation of human recombinant CYP3A4 using luciferin as substrate at 12.5 to 25 uM preincubated for 10 mins followed by substrate addition and measured after 50 mins in presence of NADPH by CYP450-Glo assay	Homo sapiens	2	ALA4433195	single protein format	Scientific Literature
20.	ALA4433307	A	Inhibition of human recombinant CYP2D6 at >2.5 uM using luciferin as substrate preincubated for 10 mins followed by substrate addition and measured after 50 mins in presence of NADPH by CYP450-Glo assay	Homo sapiens	2	ALA4433195	single protein format	Scientific Literature