# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4404492 | B | Inhibition of Enterovirus A71 protease 3C using DabcylKEALFQ-GPPQF-E(Edans)-NH2 as substrate incubated for 10 mins by fluorospectrometry | Enterovirus | 11 | assay format | Scientific Literature | ||
2. | ALA4404493 | B | Inhibition of Corona virus B3 protease 3C using DabcylKEALFQ-GPPQF-E(Edans)-NH2 as substrate incubated for 10 mins by fluorospectrometry | Coronavirus | 11 | assay format | Scientific Literature | ||
3. | ALA4404494 | B | Inhibition of SARS coronavirus M protease using Dabcyl-KTSAVLQ-SGFRKM-E(Edans)-NH2 as substrate incubated for 10 mins by fluorospectrometry | SARS coronavirus | 11 | assay format | Scientific Literature | ||
4. | ALA4404495 | B | Inhibition of human coronavirus NL63 M protease using Dabcyl-KTSAVLQ-SGFRKM-E(Edans)-NH2 as substrate incubated for 10 mins by fluorospectrometry | Human coronavirus NL63 | 11 | assay format | Scientific Literature | ||
5. | ALA4404496 | F | Antiviral activity against Enterovirus A71 infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in viral RNA replication incubated for 24 hrs by luciferase reporter gene assay | Enterovirus A71 | 10 | organism-based format | Scientific Literature | ||
6. | ALA4404497 | F | Antiviral activity against Coronavirus B3 infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in viral RNA replication incubated for 24 hrs by luciferase reporter gene assay | Coronavirus | 10 | organism-based format | Scientific Literature | ||
7. | ALA4404498 | F | Antiviral activity against SARS coronavirus infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in viral RNA replication incubated for 24 hrs by luciferase reporter gene assay | Severe acute respiratory syndrome-related coronavirus | 10 | organism-based format | Scientific Literature | ||
8. | ALA4404499 | F | Antiviral activity against Coronavirus B3 infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in virus-induced cytopathic effect incubated for 2 days by non-radioactive cell proliferation assay | Coronavirus | 6 | organism-based format | Scientific Literature | ||
9. | ALA4404500 | F | Antiviral activity against Human coronavirus 229E infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by Alamar blue based assay | Human coronavirus 229E | 6 | organism-based format | Scientific Literature | ||
10. | ALA4404501 | F | Antiviral activity against Middle East respiratory syndrome coronavirus infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in virus-induced cytopathic effect incubated for 2 days by non-radioactive cell proliferation assay | Middle East respiratory syndrome-related coronavirus | 6 | organism-based format | Scientific Literature | ||
11. | ALA4404502 | F | Antiviral activity against Middle East respiratory syndrome coronavirus infected in Vero cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by non-radioactive cell proliferation assay | Middle East respiratory syndrome-related coronavirus | 6 | organism-based format | Scientific Literature | ||
12. | ALA4404503 | F | Antiviral activity against SARS coronavirus infected in Vero E6 cells assessed as reduction in virus-induced cytopathic effect incubated for 2 days by non-radioactive cell proliferation assay | Severe acute respiratory syndrome-related coronavirus | 6 | organism-based format | Scientific Literature | ||
13. | ALA4404504 | F | Antiviral activity against Enterovirus A71 infected in RD cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS assay | Enterovirus A71 | 6 | organism-based format | Scientific Literature | ||
14. | ALA4404505 | F | Antiviral activity against Enterovirus D68 infected in HeLa Rh cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS assay | enterovirus D68 | 6 | organism-based format | Scientific Literature | ||
15. | ALA4404506 | F | Antiviral activity against Human rhinovirus 2 infected in HeLa Rh cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS assay | rhinovirus A2 | 6 | organism-based format | Scientific Literature | ||
16. | ALA4404507 | F | Antiviral activity against Human rhinovirus 14 infected in HeLa Rh cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS assay | rhinovirus B14 | 6 | organism-based format | Scientific Literature | ||
17. | ALA4404508 | A | Cytotoxicity against human HuH7 cells expressing T7 RNA polymerase assessed as reduction in cell viability incubated for 2 days by non-radioactive cell proliferation assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
18. | ALA4404509 | A | Cytotoxicity against human RD cells assessed as reduction in cell viability incubated for 3 days by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
19. | ALA4404510 | A | Cytotoxicity against human HeLa Rh cells assessed as reduction in cell viability incubated for 3 days by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
20. | ALA4404517 | T | Therapeutic index, ratio of CC50 for human HeLa Rh cells to EC50 for Enterovirus D68 infected in human HeLa Rh cells | 3 | cell-based format | Scientific Literature |