# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4428139 | B | Activation of full-length GST-tagged recombinant human SIRT1 assessed as enzyme activity obtained without subtraction of intrinsic fluorescence using H3K9 as substrate at 50 uM after 30 mins by SIRTainty assay | Homo sapiens | 56 | single protein format | Scientific Literature | ||
2. | ALA4428140 | B | Activation of full-length GST-tagged recombinant human SIRT1 assessed as enzyme activity obtained with subtraction of intrinsic fluorescence using H3K9 as substrate at 50 uM after 30 mins by SIRTainty assay | Homo sapiens | 51 | single protein format | Scientific Literature | ||
3. | ALA4428142 | B | Activation of AMPK/SIRT1 in human HaCaT cells assessed as nitric oxide production at 1 uM incubated for 1 hr by DAF-2D staining-based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA4428144 | B | Activation of AMPK/SIRT1 in human HaCaT cells assessed as nitric oxide production at 10 uM incubated for 1 hr in presence of compound C by DAF-2D staining-based fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA4428145 | B | Activation of AMPK/SIRT1 in human HaCaT cells assessed as nitric oxide production at 10 uM incubated for 1 hr in presence of EX-527 by DAF-2D staining-based fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA4428157 | F | Antiproliferative activity against human M14 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4428158 | F | Antiproliferative activity against human SAN cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4428159 | F | Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4428160 | F | Antiproliferative activity against human NCI-H1299 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4428161 | F | Antiproliferative activity against human HT-29 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA4428162 | F | Antiproliferative activity against human LoVo cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4428163 | F | Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA4428164 | F | Antiproliferative activity against human Caov3 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA4428165 | F | Antiproliferative activity against human HEY cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA4428166 | F | Antiproliferative activity against human SKOV3 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA4428167 | F | Antiproliferative activity against human A2780 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA4428168 | B | Activation of SIRT1 in human M14 cells assessed as deacetylation of acetyl-H4K16 after 48 hrs by Western blotting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4428169 | B | Activation of SIRT1 in human NCI-H1299 cells assessed as deacetylation of acetyl-H4K16 after 48 hrs by Western blotting method | Homo sapiens | 1 | cell-based format | Scientific Literature |