# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4424782 | B | Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 7 | ALA4422684 | cell-based format | Scientific Literature | |
2. | ALA4424783 | B | Potency index, ratio of CPI-455 IC50 to test compound IC50 for human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature | |
3. | ALA4424784 | B | Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
4. | ALA4424785 | B | Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
5. | ALA4424786 | B | Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(21-44)-K36(Me2)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
6. | ALA4424787 | B | Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(21-44)-K36(Me2)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
7. | ALA4424788 | B | Inhibition of human N-terminal FLAG-tagged KDM3A (2 to 1321 residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(1-21)K9(Me1)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
8. | ALA4424789 | B | Inhibition of human N-terminal FLAG-tagged KDM3A (2 to 1321 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(1-21)K9(Me1)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
9. | ALA4424790 | B | Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli at 50 uM using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | assay format | Scientific Literature | |
10. | ALA4424791 | B | Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli at 25 uM using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | assay format | Scientific Literature | |
11. | ALA4424792 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(21-44)-K27(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
12. | ALA4424793 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(21-44)-K27(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
13. | ALA4424794 | B | Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(1-21)K9(Me2)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
14. | ALA4424795 | B | Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(1-21)K9(Me2)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
15. | ALA4424796 | B | Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K36(Me2)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature | |
16. | ALA4424797 | B | Inhibition of human N-terminal FLAG-tagged KDM3A (2 to 1321 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me1)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 1 | ALA4422684 | cell-based format | Scientific Literature | |
17. | ALA4424799 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K27(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 3 | ALA4422684 | cell-based format | Scientific Literature | |
18. | ALA4424800 | B | Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me2)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature | |
19. | ALA4424801 | B | Inhibition of KDM5A in human A549 cells assessed as increase in H3K4me3 levels after 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4422684 | cell-based format | Scientific Literature | |
20. | ALA4424802 | B | Inhibition of KDM4 in human A549 cells assessed as increase in H3K9me3 levels up to 25 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature |