# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4356679 | F | Antiproliferative activity against human MCF7:5C cells assessed as reduction in cell viability incubated for 7 days by Hoechst 33258 dye based assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
2. | ALA4356680 | F | Antiproliferative activity against human MCF7:5C cells assessed as reduction in cell viability incubated for 7 days by Hoechst 33258 dye based assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA4356681 | F | Antiproliferative activity against human MCF7:WS8 cells assessed as reduction in cell viability incubated for 5 days by Hoechst 33258 dye based assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
4. | ALA4356682 | F | Antiproliferative activity against human MCF7:WS8 cells assessed as reduction in cell viability incubated for 5 days by Hoechst 33258 dye based assay relative to control | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
5. | ALA4356683 | B | Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
6. | ALA4356684 | B | Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
7. | ALA4356685 | B | Displacement of [3H]esterdiol from recombinant human full length ERalpha expressed in insect cells incubated for 45 to 90 mins by liquid scintillation counting method relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
8. | ALA4356686 | B | Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
9. | ALA4356687 | B | Selectivity index, ratio of inhibition of ERbeta to inhibition of recombinant human full length ERalpha expressed in insect cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
10. | ALA4356688 | A | Plasma concentration in C57BL/6 mouse at 100 mg/kg, po measured after 0.5 hrs by LC/MS-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
11. | ALA4356689 | A | Plasma concentration in C57BL/6 mouse at 100 mg/kg, po measured after 2 hrs by LC/MS-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
12. | ALA4356690 | A | Drug concentration in C57BL/6 mouse brain at 100 mg/kg, po measured after 0.5 hrs by LC/MS-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA4356691 | A | Drug concentration in C57BL/6 mouse brain at 100 mg/kg, po measured after 2 hrs by LC/MS-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
14. | ALA4356696 | F | Cytotoxicity against human MCF7:WS8 monolayer cells assessed as reduction in tumor spheroid size at 10 nM incubated for 10 days | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
15. | ALA4356697 | F | Cytotoxicity against human MCF7:WS8 monolayer cells assessed as reduction in tumor cell viability at 10 nM incubated for 10 days by celltiter-glo 3D cell viability assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
16. | ALA4356698 | F | Cytotoxicity against human MCF7:TAM1 monolayer cells assessed as reduction in tumor cell viability at 10 nM incubated for 10 days by celltiter-glo 3D cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
17. | ALA4670540 | T | Selectivity index, ratio of CC50 for human A549 cells to IC50 for antiviral activity against pseudotyped Marburgvirus-Musoke infected in human A549 cells | 31 | cell-based format | Scientific Literature | |||
18. | ALA4670541 | T | Selectivity index, ratio of CC50 for human A549 cells to IC50 for antiviral activity against pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells | 31 | cell-based format | Scientific Literature | |||
19. | ALA4670542 | F | Antiviral activity against pseudotyped Ebola virus - Mayinga, Zaire infected in human A549 cells assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay | Zaire ebolavirus | 31 | organism-based format | Scientific Literature | ||
20. | ALA4670543 | F | Antiviral activity against pseudotyped Marburgvirus-Musoke infected in human A549 cells assessed as reduction in viral infection incubated for 48 hrs by luciferase reporter gene assay | Marburgvirus | 31 | organism-based format | Scientific Literature |