| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4432710 | B | Inhibition of C-terminal FLAG tagged human recombinant ATX expressed in insect sf9 cells using FS-3 as substrate measured every 2 mins for 60 mins by FRET assay | Homo sapiens | 42 | ALA4431364 | cell-based format | Scientific Literature | |
| 2. | ALA4432711 | B | Inhibition of C-terminal FLAG tagged human recombinant ATX expressed in insect sf9 cells at 10 uM using FS-3 as substrate measured every 2 mins for 60 mins by FRET assay | Homo sapiens | 138 | ALA4431364 | cell-based format | Scientific Literature | |
| 3. | ALA4432712 | B | Inhibition of C-terminal FLAG tagged human recombinant ATX expressed in insect sf9 cells at 10 uM using pNP-TMP as substrate measured every 2 mins for 60 mins by fluorescence analysis | Homo sapiens | 70 | ALA4431364 | cell-based format | Scientific Literature | |
| 4. | ALA4432713 | B | Inhibition of C-terminal FLAG tagged human recombinant ATX expressed in insect sf9 cells using pNP-TMP as substrate measured every 2 mins for 60 mins by fluorescence analysis | Homo sapiens | 5 | ALA4431364 | cell-based format | Scientific Literature | |
| 5. | ALA4432714 | F | Agonist activity at LPA receptor 4 (unknown origin) assessed as calcium mobilization after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 6. | ALA4432715 | B | Inhibition of C-terminal FLAG tagged human recombinant NPP6 expressed in insect sf9 cells assessed as remaining enzyme activity response at 10 uM using pNPPC as substrate measured every 2 mins for 1 hr by fluorescence analysis | Homo sapiens | 13 | ALA4431364 | cell-based format | Scientific Literature | |
| 7. | ALA4432716 | B | Inhibition of C-terminal FLAG tagged human recombinant NPP7 expressed in insect sf9 cells assessed as remaining enzyme activity response at 10 uM using pNPPC as substrate measured every 2 mins for 1 hr by fluorescence analysis | Homo sapiens | 13 | ALA4431364 | cell-based format | Scientific Literature | |
| 8. | ALA4432718 | F | Agonist activity at LPA receptor 1 (unknown origin) assessed as calcium mobilization after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 9. | ALA4432719 | F | Agonist activity at LPA receptor 2 in double knockout MEF assessed as calcium mobilization after 30 mins by fluorescence analysis | Mus musculus | 1 | ALA4431364 | cell-based format | Scientific Literature | |
| 10. | ALA4432720 | F | Agonist activity at LPA receptor 3 (unknown origin) assessed as calcium mobilization after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 11. | ALA4432721 | F | Agonist activity at LPA receptor 5 (unknown origin) assessed as calcium mobilization after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 12. | ALA4432722 | F | Antagonist activity at LPA receptor 1 (unknown origin) assessed as inhibition of LPA induced calcium mobilization at 0.01 to 10 uM after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 13. | ALA4432723 | F | Antagonist activity at LPA receptor 2 in double knockout MEF assessed as inhibition of LPA induced calcium mobilization at 0.01 to 10 uM after 30 mins by fluorescence analysis | Mus musculus | 1 | ALA4431364 | cell-based format | Scientific Literature | |
| 14. | ALA4432724 | F | Antagonist activity at LPA receptor 3 (unknown origin) assessed as inhibition of LPA induced calcium mobilization at 0.01 to 10 uM after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 15. | ALA4432725 | F | Antagonist activity at LPA receptor 4 (unknown origin) assessed as inhibition of LPA induced calcium mobilization at 0.01 to 10 uM after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 16. | ALA4432726 | F | Antagonist activity at LPA receptor 5 (unknown origin) assessed as inhibition of LPA induced calcium mobilization at 0.01 to 10 uM after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 17. | ALA4432727 | F | Potentiation of LPA induced activity at LPA receptor 2 in double knockout MEF assessed as calcium mobilization at 0.01 to 10 uM after 30 mins in presence of BSA by Fura-2AM based fluorescence analysis | Mus musculus | 1 | ALA4431364 | cell-based format | Scientific Literature | |
| 18. | ALA4432728 | B | Potency index, ratio of IC50 for GRI392104 to IC50 for test compound for inhibition of C-terminal FLAG tagged human recombinant ATX expressed in insect sf9 cells using FS-3 as substrate measured every 2 mins for 60 mins by FRET assay | Homo sapiens | 1 | ALA4431364 | cell-based format | Scientific Literature |
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