# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4370819 | B | Inhibition of Leucyl-tRNA synthetase-mediated mTORC1 signaling activation in human HEK293 cells assessed as reduction in leucine-induced S6K phosphorylation at 200 uM preincubated for 50 mins followed by leucine-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 48 | ALA4368933 | cell-based format | Scientific Literature | |
2. | ALA4370822 | F | Antiproliferative activity against human A549 cells after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4368933 | cell-based format | Scientific Literature | |
3. | ALA4370823 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4368933 | cell-based format | Scientific Literature | |
4. | ALA4370824 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4368933 | cell-based format | Scientific Literature | |
5. | ALA4370825 | F | Antiproliferative activity against human SKHEP1 cells after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4368933 | cell-based format | Scientific Literature | |
6. | ALA4370826 | F | Antiproliferative activity against human SNU638 cells after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4368933 | cell-based format | Scientific Literature | |
7. | ALA4370827 | A | Antiproliferative activity against human MRC5 cells after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4368933 | cell-based format | Scientific Literature |