| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4400879 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells measured after 24 hrs by immunoblotting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4400880 | F | Antiproliferative activity against human 22Rv1 cells after 72 hrs by CelTiter-Glo reagent-based luminescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4400881 | B | Induction of CRBN-mediated BRD4 degradation in human U266 cells up to 1000 nM measured after 12 hrs by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4400882 | B | Induction of CRBN ubiquitin ligase-mediated IKZF1 degradation in human U266 cells up to 1000 nM measured after 12 hrs by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4400883 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells in presence of proteasome inhibitor bortezomib by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4400884 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells in presence of neddylation inhibitor MLN4924 by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4400885 | B | Induction of BRD4 degradation in CRBN knockdown human 22RV1 cells by immunoblotting analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA4400886 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells in presence of JQ1 by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4400887 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells in presence of TD-106 by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4400888 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells assessed as downregulation of c-Myc protein expression up to 1000 nM by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4400892 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells assessed as BRD4 protein remaining at 10'-1 nM measured after 24 hrs by immunoblotting analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA4400893 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells assessed as BRD4 protein remaining at 1 nM measured after 24 hrs by immunoblotting analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 13. | ALA4400894 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells assessed as BRD4 protein remaining at 10 nM measured after 24 hrs by immunoblotting analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA4400895 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells assessed as BRD4 protein remaining at 100 nM measured after 24 hrs by immunoblotting analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA4400896 | B | Induction of CRBN-mediated BRD4 degradation in human 22RV1 cells assessed as BRD4 protein remaining at 1000 nM measured after 24 hrs by immunoblotting analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA4400897 | B | Induction of CRBN-mediated BRD3 degradation in human 22RV1 cells up to 1000 nM measured after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4400898 | B | Induction of CRBN-mediated BRD2 degradation in human 22RV1 cells up to 1000 nM measured after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4400899 | B | Induction of CRBN ubiquitin ligase-mediated IKZF3 degradation in human U266 cells up to 1000 nM measured after 12 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4400900 | B | Induction of Xpress-tagged CRBN (unknown origin)/FALG-tagged BRD4 (unknown origin) protein-protein interaction by immunoblotting analysis | Homo sapiens | 1 | protein format | Scientific Literature |
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