# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406121 | Functional | Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
2. | ALA4406122 | Functional | Cytotoxicity in human A375 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
3. | ALA4406123 | Functional | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
4. | ALA4406124 | Functional | Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
5. | ALA4406125 | Functional | Cytotoxicity in human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
6. | ALA4406127 | Functional | Cytotoxicity in human Caov3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
7. | ALA4406128 | Binding | Binding affinity to CDC20 (unknown origin) by SPR analysis | Homo sapiens | 4 | ALA4402600 | single protein format | Scientific Literature | |
8. | ALA4406129 | Binding | Inhibition of CDC20 in human HepG2 cells assessed as increase in Bim protein levels at 30 uM incubated for 48 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
9. | ALA4406131 | Binding | Inhibition of CDC20 in human HepG2 cells assessed as decrease in cyclin B degradation at 30 uM incubated for 48 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
10. | ALA4406132 | Binding | Inhibition of CDH1 in human HepG2 cells assessed as effect on Aurora A protein expression at 30 uM incubated for 48 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
11. | ALA4406133 | Binding | Inhibition of CDH1 in human HepG2 cells assessed as effect on Skp2 protein expression at 30 uM incubated for 48 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
12. | ALA4406134 | Binding | Inhibition of CDC20 in human HepG2 cells assessed as increase in stability of Bim protein at 30 uM measured after 2 to 8 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
13. | ALA4406135 | Binding | Inhibition of CDC20 in human HepG2 cells assessed as increase in stability of cyclin B1 protein at 30 uM measured after 2 to 8 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
14. | ALA4406136 | Binding | Inhibition of CDC20 in human HepG2 cells assessed as increase in Aurora A protein degradation at 30 uM measured after 1 to 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
15. | ALA4406137 | Binding | Inhibition of CDC20 in human HepG2 cells assessed as increase in stability of Bim protein at 0.3 uM measured after 1 to 12 hrs by Western blot Analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
16. | ALA4406138 | Functional | Inhibition of mitotic exit in human HepG2 cells assessed as increase in nuclear phosphohistone H3 levels incubated for 48 hrs by immunofluorescence assay | Homo sapiens | 3 | ALA4402600 | cell-based format | Scientific Literature | |
17. | ALA4406139 | Functional | Inhibition of mitotic exit in human HepG2 cells assessed as increase in nuclear phosphohistone H3 levels at 30 uM incubated for 48 hrs by immunofluorescence assay relative to control | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
18. | ALA4406142 | Functional | Inhibition of mitotic exit in human HepG2 cells assessed as increase in nuclear phosphohistone H3 levels at 3 to 30 uM incubated for 48 hrs by by Western blot analysis relative to control | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
19. | ALA4406150 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in cleaved PARP level at 3 to 30 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
20. | ALA4406151 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in cleaved caspase-3 level at 3 to 30 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature |