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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4481835 F Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue method Mycobacterium tuberculosis 25 organism-based format Scientific Literature 2. ALA4481836 B Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF as substrate preincubated for 1 min followed by DHF addition and measured for 2 mins by spectrophotometric method Mycobacterium tuberculosis H37Rv 4 assay format Scientific Literature 3. ALA4481837 A Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate preincubated for 1 min followed by DHF addition and measured for 2 mins by spectrophotometric method Homo sapiens 3 single protein format Scientific Literature 4. ALA4481838 T Selectivity index, ratio of IC50 for human DHFR to IC50 for Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) 3 assay format Scientific Literature 5. ALA4481839 T Sub-acute toxicity in albino Wistar rat assessed as adverse effect at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 6. ALA4481840 T Sub-acute toxicity in albino Wistar rat assessed as effect on clinical changes at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 7. ALA4481841 T Sub-acute toxicity in albino Wistar rat assessed as effect on behavioral changes at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 8. ALA4481842 T Sub-acute toxicity in albino Wistar rat assessed as mortality at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 9. ALA4481843 T Sub-acute toxicity in albino Wistar rat assessed as effect on water intake at 1.25 to 10 mg/kg, po administered for 28 days measured post last dose Rattus norvegicus 1 organism-based format Scientific Literature 10. ALA4481844 T Sub-acute toxicity in albino Wistar rat assessed as effect on food intake at 1.25 to 10 mg/kg, po administered for 28 days measured post last dose Rattus norvegicus 1 organism-based format Scientific Literature 11. ALA4481845 T Sub-acute toxicity in albino Wistar rat assessed as change in body weight at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 12. ALA4481846 T Sub-acute toxicity in albino Wistar rat assessed as effect on neurological changes at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 13. ALA4481847 T Sub-acute toxicity in albino Wistar rat assessed as convulsion at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 14. ALA4481848 T Sub-acute toxicity in albino Wistar rat assessed as salivation at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 15. ALA4481849 T Sub-acute toxicity in albino Wistar rat assessed as effect on sleep at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 16. ALA4481850 T Sub-acute toxicity in albino Wistar rat assessed as tremors at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 17. ALA4481851 T Sub-acute toxicity in albino Wistar rat assessed as diarrhea at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 18. ALA4481852 T Sub-acute toxicity in albino Wistar rat assessed as lethargy at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 19. ALA4481853 T Sub-acute toxicity in albino Wistar rat assessed as coma at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature 20. ALA4481854 T Sub-acute toxicity in albino Wistar rat assessed as change in colour at 1.25 to 10 mg/kg, po administered for 28 days Rattus norvegicus 1 organism-based format Scientific Literature