# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4353460 | Binding | Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as upregulation of MDM2 expression at 1 uM measured after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4350988 | cell-based format | Scientific Literature | |
2. | ALA4353461 | Binding | Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as upregulation of P21 expression at 1 uM measured after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4350988 | cell-based format | Scientific Literature | |
3. | ALA4353464 | Binding | Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as effect on TP53 expression at 1 uM measured after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4350988 | cell-based format | Scientific Literature | |
4. | ALA4353471 | Functional | Induction of apoptosis in human RS4:11 cells assessed as viable cells at 10 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
5. | ALA4353472 | Functional | Induction of apoptosis in human RS4:11 cells assessed as early apoptotic cells at 10 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
6. | ALA4353473 | Functional | Induction of apoptosis in human RS4:11 cells assessed as late apoptotic cells at 10 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
7. | ALA4353474 | Functional | Induction of apoptosis in human RS4:11 cells assessed as necrotic cells at 10 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
8. | ALA4353475 | Functional | Induction of apoptosis in human RS4:11 cells assessed as viable cells at 100 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
9. | ALA4353476 | Functional | Induction of apoptosis in human RS4:11 cells assessed as early apoptotic cells at 100 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
10. | ALA4353477 | Functional | Induction of apoptosis in human RS4:11 cells assessed as late apoptotic cells at 100 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
11. | ALA4353478 | Functional | Induction of apoptosis in human RS4:11 cells assessed as necrotic cells at 100 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
12. | ALA4353479 | Functional | Induction of apoptosis in human RS4:11 cells assessed as viable cells at 1000 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
13. | ALA4353480 | Functional | Induction of apoptosis in human RS4:11 cells assessed as early apoptotic cells at 1000 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
14. | ALA4353481 | Functional | Induction of apoptosis in human RS4:11 cells assessed as late apoptotic cells at 1000 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature | |
15. | ALA4353482 | Functional | Induction of apoptosis in human RS4:11 cells assessed as necrotic cells at 1000 nM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4350988 | cell-based format | Scientific Literature |