| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4395390 | B | Binding affinity to G-quadruplex G2 DNA (unknown origin) assessed as change in melting temperature at compound to DNA ratio of 7:1 by fluorescence thermal denaturation analysis | Not specified | 2 | nucleic acid format | Scientific Literature | ||
| 2. | ALA4395392 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 100 mM K+ by circular dichroism thermal denaturation analysis (Rvb= 52.6 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
| 3. | ALA4395393 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 150 mM Na+ by circular dichroism thermal denaturation analysis (Rvb = 57.4 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
| 4. | ALA4395394 | B | Binding affinity to human G-quadruplex G1 DNA assessed as equilibrium dissociation constant at 0.5 uM incubated for 30 mins under dark condition by fluorometric titration analysis | Homo sapiens | 7 | nucleic acid format | Scientific Literature | ||
| 5. | ALA4395395 | B | Ratio of thiazole orange Kd to compound Kd for human G-quadruplex G1 DNA at 0.5 uM incubated for 30 mins in dark by fluorimetric titration analysis | Homo sapiens | 1 | nucleic acid format | Scientific Literature | ||
| 6. | ALA4395396 | B | Binding affinity to 17 mer duplex D1 DNA (unknown origin) assessed as equilibrium dissociation constant at 0.5 uM incubated for 30 mins under dark condition by fluorometric titration analysis | Not specified | 7 | nucleic acid format | Scientific Literature | ||
| 7. | ALA4395397 | B | Ratio of Kd for human G-quadruplex G1 DNA to Kd for 17 mer duplex D1 DNA (unknown origin) by flourimetric titration analysis | 7 | assay format | Scientific Literature | |||
| 8. | ALA4395402 | B | Inhibition of telomerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay relative to control | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 9. | ALA4395403 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay relative to control | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 10. | ALA4395404 | B | Inhibition of telomerase activity in human HeLa cell lysate at 10 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 5 | subcellular format | Scientific Literature | ||
| 11. | ALA4395405 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 10 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 3 | subcellular format | Scientific Literature | ||
| 12. | ALA4395407 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 5 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 13. | ALA4395408 | B | Inhibition of telomerase activity in human HeLa cell lysate at 0.156 to 2.5 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 14. | ALA4395409 | B | Inhibition of telomerase activity in human HeLa cell lysate at 0.078 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 15. | ALA4395414 | B | Binding affinity to human G-quadruplex G1 DNA assessed as increase in fluorescence at 0.5 uM incubated for 30 mins in dark by fluorescence titration analysis relative to control | Homo sapiens | 7 | nucleic acid format | Scientific Literature | ||
| 16. | ALA4395417 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 0.156 to 2.5 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 17. | ALA4395421 | B | Inhibition of telomerase activity in human HeLa cell lysate at 5 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 1 | subcellular format | Scientific Literature |
The page will load shortly, Thanks for your patience!