| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4376261 | B | Inhibition of Pseudomonas aeruginosa tRNA (guanine(37)-N1)-methyltransferase (Leu5 to Asp25 residues) expressed in Escherichia coli BL21 (DE3) Rosetta T1R cells assessed as reduction in S-adenosyl-L-homocysteine production preincubated for 15 mins followed by 1.5 uM of tRNALeu(CAG) substrate and SAM addition and measured after 45 mins by MTase-Glo assay | Pseudomonas aeruginosa | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA4376283 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 at 100 uM incubated for 24 hrs | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
| 3. | ALA4376284 | F | Antibacterial activity against Enterococcus faecalis ATCC 51299 at 100 uM incubated for 24 hrs | Enterococcus faecalis | 25 | organism-based format | Scientific Literature | ||
| 4. | ALA4376285 | F | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 at 100 uM incubated for 24 hrs | Streptococcus pneumoniae | 25 | organism-based format | Scientific Literature | ||
| 5. | ALA4376286 | F | Antibacterial activity against Mycolicibacterium smegmatis MC2 155 at 100 uM incubated for 24 hrs | Mycolicibacterium smegmatis | 25 | organism-based format | Scientific Literature | ||
| 6. | ALA4376287 | F | Antibacterial activity against Mycobacterium tuberculosis ATCC 27294 at 100 uM incubated for 7 days | Mycobacterium tuberculosis | 25 | organism-based format | Scientific Literature | ||
| 7. | ALA4376288 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 incubated for 24 hrs by serial broth microdilution method | Pseudomonas aeruginosa | 9 | organism-based format | Scientific Literature | ||
| 8. | ALA4376289 | F | Antibacterial activity against Acinetobacter baumannii ATCC 17961 incubated for 24 hrs by serial broth microdilution method | Acinetobacter baumannii | 9 | organism-based format | Scientific Literature | ||
| 9. | ALA4376290 | F | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 24 hrs by serial broth microdilution method | Klebsiella pneumoniae | 9 | organism-based format | Scientific Literature | ||
| 10. | ALA4376291 | F | Antibacterial activity against Salmonella enteritidis ATCC 13076 incubated for 24 hrs by serial broth microdilution method | Salmonella enterica subsp. enterica serovar Enteritidis | 9 | organism-based format | Scientific Literature | ||
| 11. | ALA4376292 | F | Antibacterial activity against Escherichia coli BW25113 incubated for 24 hrs by serial broth microdilution method | Escherichia coli | 9 | organism-based format | Scientific Literature | ||
| 12. | ALA4376293 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 incubated for 24 hrs by serial broth microdilution method | Staphylococcus aureus | 9 | organism-based format | Scientific Literature | ||
| 13. | ALA4376294 | F | Antibacterial activity against Enterococcus faecalis ATCC 51299 incubated for 24 hrs by serial broth microdilution method | Enterococcus faecalis | 9 | organism-based format | Scientific Literature | ||
| 14. | ALA4376295 | F | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 incubated for 24 hrs by serial broth microdilution method | Streptococcus pneumoniae | 9 | organism-based format | Scientific Literature | ||
| 15. | ALA4376296 | F | Antibacterial activity against Mycolicibacterium smegmatis MC2 155 incubated for 24 hrs by serial broth microdilution method | Mycolicibacterium smegmatis | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4376297 | F | Antibacterial activity against Mycobacterium tuberculosis ATCC 27294 incubated for 7 days by broth dilution method | Mycobacterium tuberculosis | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4376298 | F | Bactericidal activity against Pseudomonas aeruginosa PA14 assessed as reduction in CFU at 1 to 4 times MIC90 incubated for 24 hrs | Pseudomonas aeruginosa | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA4376299 | F | Bactericidal activity against Acinetobacter baumannii ATCC 17961 assessed as reduction in CFU at 1 to 4 times MIC90 incubated for 24 hrs | Acinetobacter baumannii | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA4376300 | F | Bactericidal activity against Klebsiella pneumoniae ATCC 13883 assessed as reduction in CFU at 1 to 4 times MIC90 incubated for 24 hrs | Klebsiella pneumoniae | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA4376301 | F | Bactericidal activity against Salmonella enteritidis ATCC 13076 assessed as reduction in CFU at 1 to 4 times MIC90 incubated for 24 hrs | Salmonella enterica subsp. enterica serovar Enteritidis | 3 | organism-based format | Scientific Literature |
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