| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4346578 | B | Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 2. | ALA4346580 | B | Inhibition of PRMT6 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA4346582 | B | Time dependent inhibition of human PRMT6 pre-incubated for 1 to 30 mins using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4346583 | B | Reversible inhibition of human PRMT6 pre-incubated for 1 to 30 mins using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4346584 | B | Covalent binding affinity to human PRMT6 assessed as covalent adduct. formation at 300 uM pre-incubated for 1 hr by mass spectrometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA4346589 | B | Inhibition of human PRMT1 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA4346590 | B | Inhibition of human PRMT3 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA4346591 | B | Inhibition of human PRMT4 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA4346592 | B | Inhibition of human PRMT8 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 10. | ALA4346599 | B | Inhibition of Flag-tagged PRMT6 (unknown origin) expressed in HEK293 cells at 0.1 to 10 uM incubated for 20 hrs assessed as reduction in H3R2me2a levels | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4346600 | B | Inhibition of PRMT1 in human MCF7 cells assessed as reduction in H4R3me2a levels incubated for 2 days by fluorescence based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4346602 | B | Inhibition of PRMT3 (unknown origin) expressed in HEK293T cells were co-transfected with GFP-tagged histone H4 peptide assessed as reduction in H4R3 arginine asymmetric dimethylation at 0.2 to 20 uM incubated for 20 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4346605 | B | Inhibition of PRMT4 in human MCF7 cells assessed as reduction in BAF155 asymmetric dimethylation at 0.2 to 20 uM incubated for 2 days | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4346608 | T | Toxicity in human MCF7 cells assessed as reduction in cell viability up to 20 uM incubated for 3 days by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4346609 | T | Toxicity in human PNT2 cells assessed as reduction in cell viability up to 20 uM incubated for 3 days by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4346610 | T | Toxicity in HEK293T cells assessed as reduction in cell viability up to 20 uM incubated for 3 days by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4346611 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA4346612 | B | Inhibition of PRMT3 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 19. | ALA4346613 | B | Inhibition of PRMT4 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA4346616 | B | Inhibition of PRMT8 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature |
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