| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4388580 | B | Protac activity at VHL/c-ABL in human K562 cells assessed as induction of c-ABL protein degradation incubated for 24 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4388600 | B | Protac activity at VHL/c-ABL in human K562 cells assessed as induction of c-ABL protein degradation at 1 uM incubated for 24 hrs by immunoblot method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4415963 | F | Growth inhibition of human K562 cells incubated for 2 days by CCK8 assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA4415964 | B | Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation at 10 uM by Western blot analysis | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 5. | ALA4672969 | B | Protac binding affinity at VHL/BCR-ABL (unknown origin) assessed as binding to phosphorylated c-ABL kinase domain by Kinomescan assay | Homo sapiens | 5 | protein format | Scientific Literature | ||
| 6. | ALA4672971 | B | Protac binding affinity at VHL/BCR-ABL (unknown origin) assessed as binding to non phosphorylated c-ABL kinase domain by Kinomescan assay | Homo sapiens | 5 | protein format | Scientific Literature |
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