# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4388580 | Binding | Protac activity at VHL/c-ABL in human K562 cells assessed as induction of c-ABL protein degradation incubated for 24 hrs by immunoblot method | Homo sapiens | 1 | ALA4387721 | cell-based format | Scientific Literature | |
2. | ALA4388600 | Binding | Protac activity at VHL/c-ABL in human K562 cells assessed as induction of c-ABL protein degradation at 1 uM incubated for 24 hrs by immunoblot method relative to control | Homo sapiens | 1 | ALA4387721 | cell-based format | Scientific Literature | |
3. | ALA4415963 | Functional | Growth inhibition of human K562 cells incubated for 2 days by CCK8 assay | Homo sapiens | 21 | ALA4414590 | cell-based format | Scientific Literature | |
4. | ALA4415964 | Binding | Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation at 10 uM by Western blot analysis | Homo sapiens | 14 | ALA4414590 | cell-based format | Scientific Literature | |
5. | ALA4672969 | Binding | Protac binding affinity at VHL/BCR-ABL (unknown origin) assessed as binding to phosphorylated c-ABL kinase domain by Kinomescan assay | Homo sapiens | 5 | ALA4665907 | protein format | Scientific Literature | |
6. | ALA4672971 | Binding | Protac binding affinity at VHL/BCR-ABL (unknown origin) assessed as binding to non phosphorylated c-ABL kinase domain by Kinomescan assay | Homo sapiens | 5 | ALA4665907 | protein format | Scientific Literature |