#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4478550	B	Inhibition of mRNA splicing of SMN2 exon 7 in fibroblasts derived from human SMA type 1/2/3 patient assessed as increase in SMN protein level after 48 hrs by HTRF assay	Homo sapiens	18	ALA4477215	assay format	Scientific Literature
2.	ALA4478551	T	Mutagenicity in Salmonella typhimurium TA1535 assessed as increase in revertant colonies after 2 days in presence of rat liver S9 fraction by Ames test relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	16	ALA4477215	subcellular format	Scientific Literature
3.	ALA4478552	T	Mutagenicity in Salmonella typhimurium TA98 assessed as increase in revertant colonies after 2 days in presence of rat liver S9 fraction by Ames test relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	16	ALA4477215	subcellular format	Scientific Literature
4.	ALA4478553	T	Mutagenicity in Salmonella typhimurium TA97 assessed as increase in revertant colonies after 2 days in presence of rat liver S9 fraction by Ames test relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	16	ALA4477215	subcellular format	Scientific Literature
5.	ALA4478554	T	Mutagenicity in Salmonella typhimurium TA100 assessed as increase in revertant colonies after 2 days in presence of rat liver S9 fraction by Ames test relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	16	ALA4477215	subcellular format	Scientific Literature
6.	ALA4478555	T	Mutagenicity in Salmonella typhimurium TA102 assessed as increase in revertant colonies after 2 days in presence of rat liver S9 fraction by Ames test relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	16	ALA4477215	subcellular format	Scientific Literature
7.	ALA4478556	B	Inhibition of mRNA splicing of SMN2 exon 7 in GM03813 fibroblasts derived from human SMA type 1 patient after 24 hrs by RT-qPCR analysis	Homo sapiens	16	ALA4477215	assay format	Scientific Literature
8.	ALA4478557	F	Phototoxicity in mouse 3T3 cells in presence of UVA irradiation	Mus musculus	3	ALA4477215	cell-based format	Scientific Literature
9.	ALA4478606	A	Stability of the compound in human plasma	Homo sapiens	1	ALA4477215	cell-free format	Scientific Literature
10.	ALA4478607	P	Stability of the compound in pH 1 to 12 aqueous buffer		1	ALA4477215	small-molecule physicochemical format	Scientific Literature
11.	ALA4478610	B	Inhibition of mRNA splicing of human SMN2 exon 7 transfected in HEK293H cells assessed as compound concentration required to increase full-length SMN2 mRNA level by 1.5 times after 24 hrs by RT-qPCR analysis relative to GAPDH	Homo sapiens	57	ALA4477216	cell-based format	Scientific Literature
12.	ALA4478614	B	Inhibition of mRNA splicing of SMN2 exon 7 in GM03813 fibroblasts derived from SMA patient assessed as compound concentration required to increase SMN protein level by 1.5 times after 24 hrs by HTRF assay	Homo sapiens	59	ALA4477216	assay format	Scientific Literature
13.	ALA4478616	A	Apparent permeability in human Caco2 cells	Homo sapiens	7	ALA4477216	cell-based format	Scientific Literature
14.	ALA4478617	A	Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in human Caco2 cells	Homo sapiens	7	ALA4477216	cell-based format	Scientific Literature
15.	ALA4478618	A	Protein binding in human plasma	Homo sapiens	7	ALA4477216	cell-free format	Scientific Literature
16.	ALA4478619	A	AUC (0 to 6 hrs) in Sprague-Dawley rat at 10 mg/kg, po	Rattus norvegicus	11	ALA4477216	organism-based format	Scientific Literature
17.	ALA4478620	A	Ratio of drug level in brain to plasma of Sprague-Dawley rat at 10 mg/kg, po measured at 6 hrs	Rattus norvegicus	11	ALA4477216	organism-based format	Scientific Literature
18.	ALA4478621	A	AUC (0 to 24 hrs) in FVB.Cg-Tg(SMN2 delta 7 exon)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J mouse at 10 mg/kg, ip	Mus musculus	3	ALA4477216	organism-based format	Scientific Literature
19.	ALA4478622	A	Ratio of drug level in brain to plasma of FVB.Cg-Tg(SMN2 delta 7 exon)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J mouse at 10 mg/kg, ip	Mus musculus	3	ALA4477216	organism-based format	Scientific Literature
20.	ALA4478628	F	In vivo inhibition of mRNA splicing of human SMN2 exon 7 in FVB.Cg-Tg(SMN2 delta 7 exon)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J mouse assessed as median survival time at 1 mg/kg/day, ip administered on postnatal day 3 to day 23 (Rvb = 14 days)	Mus musculus	2	ALA4477216	organism-based format	Scientific Literature