# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4407552 | F | Antibacterial activity against wild-type Acinetobacter baumannii ATCC 19606 measured after 18 to 20 hrs by broth microdilution method | Acinetobacter baumannii | 20 | ALA4406811 | organism-based format | Scientific Literature | |
2. | ALA4407553 | B | Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells using biotin as substrate by spectroscopic analysis | Pseudomonas aeruginosa PAO1 | 20 | ALA4406811 | cell-based format | Scientific Literature | |
3. | ALA4407554 | F | Antibacterial activity against Escherichia coli DM4100 measured after 18 to 20 hrs by broth microdilution method | Escherichia coli | 20 | ALA4406811 | organism-based format | Scientific Literature | |
4. | ALA4407555 | F | Antibacterial activity against Klebsiella pneumoniae ATCC 43816 measured after 18 to 20 hrs by broth microdilution method | Klebsiella pneumoniae | 20 | ALA4406811 | organism-based format | Scientific Literature | |
5. | ALA4407556 | F | Antibacterial activity against Pseudomonas aeruginosa PAO1 measured after 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 20 | ALA4406811 | organism-based format | Scientific Literature | |
6. | ALA4407557 | F | Antibacterial activity against Escherichia coli DM4100 measured after 18 to 20 hrs in presence of permeabilizing agent PMBN by broth microdilution method | Escherichia coli | 20 | ALA4406811 | organism-based format | Scientific Literature | |
7. | ALA4407558 | F | Ratio of MIC for Escherichia coli DM4100 in absence of permeabilizing agent PMBN to MIC for Escherichia coli DM4100 in presence of permeabilizing agent PMBN | Escherichia coli | 21 | ALA4406811 | organism-based format | Scientific Literature | |
8. | ALA4407559 | F | Antibacterial activity against Escherichia coli DM4100 harboring deltatolC mutant measured after 18 to 20 hrs by broth microdilution method | Escherichia coli | 20 | ALA4406811 | organism-based format | Scientific Literature | |
9. | ALA4407560 | F | Ratio of MIC for Escherichia coli DM4100 to MIC for Escherichia coli DM4100 harboring deltatolC mutant | Escherichia coli | 20 | ALA4406811 | organism-based format | Scientific Literature | |
10. | ALA4407561 | F | Antibacterial activity against Escherichia coli DM4100 harboring deltatolC mutant measured after 18 to 20 hrs in presence of permeabilizing agent PMBN by broth microdilution method | Escherichia coli | 20 | ALA4406811 | organism-based format | Scientific Literature | |
11. | ALA4407562 | F | Antibacterial activity against Pseudomonas aeruginosa PAO1 PAM1262 harboring MexAB-OprM/MexCD-OprJ/MexEF-OprN deletion mutant measured after 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 20 | ALA4406811 | organism-based format | Scientific Literature | |
12. | ALA4407564 | F | Ratio of MIC for Pseudomonas aeruginosa PAO1 PAM1262 harboring MexAB-OprM/MexCD-OprJ/MexEF-OprN deletion mutant in absence of permeabilizing agent PMBN to Pseudomonas aeruginosa PAO1 PAM1262 harboring MexAB-OprM/MexCD-OprJ/MexEF-OprN deletion mutant in presence of permeabilizing agent PMBN | Pseudomonas aeruginosa | 17 | ALA4406811 | organism-based format | Scientific Literature | |
13. | ALA4407567 | F | Induction of cytological changes in Escherichia coli ATCC 25922 assessed as formation of short chains of three to eight cells at 15 ug/ml measured after 2 hrs by FM 4-64/DAPI staining based microscopic analysis | Escherichia coli | 1 | ALA4406811 | organism-based format | Scientific Literature | |
14. | ALA4407568 | A | Inhibition of full-length recombinant human His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 02 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature | |
15. | ALA4407569 | A | Inhibition of full-length recombinant human C-terminal His-tagged FYN cytoplasmic domain expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 02 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature | |
16. | ALA4407570 | A | Inhibition of full-length recombinant human C-terminal His-tagged SRC cytoplasmic domain expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 02 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature | |
17. | ALA4407571 | A | Inhibition of full-length recombinant human His-tagged BTK cytoplasmic domain expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 01 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature | |
18. | ALA4407572 | A | Inhibition of recombinant human His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 04 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature | |
19. | ALA4407573 | A | Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 04 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature | |
20. | ALA4407574 | A | Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system at 25 uM using FRET-labeled Ser/Thr 07 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control | Homo sapiens | 3 | ALA4406811 | assay format | Scientific Literature |