# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4397500 | Functional | Agonist activity at recombinant human V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay | Homo sapiens | 43 | ALA4396873 | cell-based format | Scientific Literature | |
2. | ALA4397503 | Binding | Agonist activity at recombinant human V1B receptor expressed in HEK293 cells measured after 5 hrs by luciferase reporter gene assay | Homo sapiens | 43 | ALA4396873 | cell-based format | Scientific Literature | |
3. | ALA4397506 | Binding | Selectivity ratio of EC50 for recombinant human V1B receptor expressed in HEK293 cells to EC50 for recombinant human V2 receptor expressed in HEK293 cells | Homo sapiens | 43 | ALA4396873 | cell-based format | Scientific Literature | |
4. | ALA4397507 | ADME | Agonist activity at recombinant human V1a receptor expressed in HEK293 cells up to 1000 nM measured after 5 hrs by luciferase reporter gene assay | Homo sapiens | 43 | ALA4396873 | cell-based format | Scientific Literature | |
5. | ALA4397508 | ADME | Clearance in Sprague-Dawley rat at 0.1 mg/kg, iv administered as cassette dose by LC-MS/MS analysis | Rattus norvegicus | 43 | ALA4396873 | organism-based format | Scientific Literature | |
6. | ALA4397509 | ADME | Non-renal clearance in nephrectomized Sprague-Dawley rat at 0.1 mg/kg, iv administered as cassette dose by LC-MS/MS analysis | Rattus norvegicus | 43 | ALA4396873 | organism-based format | Scientific Literature | |
7. | ALA4397510 | ADME | Protein binding in rat plasma at 200 to 1000 ng/ml measured after 15 mins by UC-LC/MS/MS analysis | Rattus norvegicus | 43 | ALA4396873 | cell-free format | Scientific Literature | |
8. | ALA4397511 | Binding | Agonist activity at human OTR stably expressed in CHOK1 cells up to 10000 nM by NFAT-luciferase reporter gene assay | Homo sapiens | 31 | ALA4396873 | cell-based format | Scientific Literature |