| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4373194 | B | Inhibition of recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli preincubated for 30 mins followed by Boc-QAR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 2. | ALA4373195 | B | Inhibition of recombinant human C-terminal His10-tagged hepsin catalytic domain preincubated for 30 mins followed by Boc-QAR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 3. | ALA4373196 | B | Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 4. | ALA4373197 | B | Selectivity ratio of Ki(app) for recombinant human C-terminal His10-tagged hepsin catalytic domain to Ki(app) for recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 5. | ALA4373199 | B | Inhibition of hepsin (unknown origin) expressed in MCF10A cells preincubated for 30 mins followed by Boc-QAR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4373200 | B | Inhibition of hepsin (unknown origin) expressed in MCF10A cells assessed as reduction in desmosomal cadherin desmoglein 2 loss at 1 uM after 45 mins by Hoechst 33258 staining based immunofluorescence microscopic method | Homo sapiens | 2 | cell-based format | Scientific Literature |
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