| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4358236 | Binding | Displacement of [3H]N/OFQ from human NOP expressed in CHO cell membrane incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 21 | ALA4354845 | cell-based format | Scientific Literature | |
| 2. | ALA4358237 | Binding | Displacement of [3H]DAMGO from human MOP expressed in CHO cell membrane incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 21 | ALA4354845 | cell-based format | Scientific Literature | |
| 3. | ALA4358238 | Binding | Displacement of [3H]DPDPE from human DOP expressed in CHO cell membrane incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 21 | ALA4354845 | cell-based format | Scientific Literature | |
| 4. | ALA4358239 | Binding | Displacement of [3H]U69593 from human KOP expressed in CHO cell membrane incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 21 | ALA4354845 | cell-based format | Scientific Literature | |
| 5. | ALA4358240 | Functional | Agonist activity at human NOP expressed in CHO cell membrane incubated for 60 mins by [35S]GTPgammaS binding assay | Homo sapiens | 21 | ALA4354845 | cell-based format | Scientific Literature | |
| 6. | ALA4358241 | Functional | Agonist activity at human MOP expressed in CHO cell membrane incubated for 60 mins by [35S]GTPgammaS binding assay | Homo sapiens | 21 | ALA4354845 | cell-based format | Scientific Literature | |
| 7. | ALA4358242 | Functional | Agonist activity at human NOP expressed in CHO cell membrane incubated for 60 mins by [35S]GTPgammaS binding assay relative to N/OFQ | Homo sapiens | 20 | ALA4354845 | cell-based format | Scientific Literature | |
| 8. | ALA4358243 | Functional | Agonist activity at human MOP expressed in CHO cell membrane incubated for 60 mins by [35S]GTPgammaS binding assay relative to DAMGO | Homo sapiens | 5 | ALA4354845 | cell-based format | Scientific Literature | |
| 9. | ALA4358244 | Binding | Selectivity index, ratio of Ki for human MOP expressed in CHO cell membrane to Ki for human NOP expressed in CHO cell membrane | Homo sapiens | 5 | ALA4354845 | cell-based format | Scientific Literature | |
| 10. | ALA4358247 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells by HPLC-MS/MS analysis | Homo sapiens | 4 | ALA4354845 | cell-based format | Scientific Literature | |
| 11. | ALA4358248 | ADME | Apparent permeability across basolateral to apical side in human Caco2 cells by HPLC-MS/MS analysis | Homo sapiens | 4 | ALA4354845 | cell-based format | Scientific Literature | |
| 12. | ALA4358249 | ADME | Efflux ratio of apparent permeability across basolateral to apical side to apical to basolateral side in human Caco2 cells by HPLC-MS/MS analysis | Homo sapiens | 4 | ALA4354845 | cell-based format | Scientific Literature | |
| 13. | ALA4358250 | ADME | Apparent permeability across apical to basolateral side in dog MDCK-MDR1 cells by HPLC-MS/MS analysis | Canis lupus familiaris | 4 | ALA4354845 | cell-based format | Scientific Literature | |
| 14. | ALA4358251 | ADME | Apparent permeability across basolateral to apical side in dog MDCK-MDR1 cells by HPLC-MS/MS analysis | Canis lupus familiaris | 4 | ALA4354845 | cell-based format | Scientific Literature | |
| 15. | ALA4358252 | ADME | Efflux ratio of apparent permeability across basolateral to apical side to apical to basolateral side in dog MDCK-MDR1 cells by HPLC-MS/MS analysis | Canis lupus familiaris | 4 | ALA4354845 | cell-based format | Scientific Literature | |
| 16. | ALA4358253 | ADME | Stability in human liver microsomes assessed as half life at 1 uM incubated for 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4354845 | microsome format | Scientific Literature | |
| 17. | ALA4358254 | ADME | Stability in rat liver microsomes assessed as half life at 1 uM incubated for 60 mins by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA4354845 | microsome format | Scientific Literature | |
| 18. | ALA4358256 | ADME | Cmax in Sprague-Dawley rat plasma at 3 mg/kg, sc measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | ALA4354845 | organism-based format | Scientific Literature | |
| 19. | ALA4358257 | ADME | Tmax in Sprague-Dawley rat plasma at 3 mg/kg, sc measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | ALA4354845 | organism-based format | Scientific Literature | |
| 20. | ALA4358258 | ADME | AUClast in Sprague-Dawley rat plasma at 3 mg/kg, sc measured upto 8 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | ALA4354845 | organism-based format | Scientific Literature |
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