# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4431870 | Functional | Antimalarial activity against Plasmodium falciparum NF54 infected in human erythrocytes assessed as [3H]-hypoxanthine incorporation by scintillation counting analysis | Plasmodium falciparum | 19 | ALA4431313 | organism-based format | Scientific Literature | |
2. | ALA4431871 | ADME | Cytotoxicity against rat L6 cells after 72 hrs by alamar blue assay | Rattus norvegicus | 19 | ALA4431313 | cell-based format | Scientific Literature | |
3. | ALA4431872 | Binding | Binding affinity to recombinant Plasmodium falciparum Hsp90 expressed in Escherichia coli BL21(DE3) pLysS assessed as thermophoresis shift at 50 uM by microscale thermophoresis assay | Plasmodium falciparum | 19 | ALA4431313 | assay format | Scientific Literature | |
4. | ALA5254148 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 16 to 29 hrs | Escherichia coli | 15 | ALA5252545 | organism-based format | Scientific Literature | |
5. | ALA5254149 | Functional | Antifungal activity against Candida albicans assessed as inhibition of extracellular acidification measured after 12 mins in presence of glucose | Candida albicans | 7 | ALA5252545 | organism-based format | Scientific Literature | |
6. | ALA5254150 | Functional | Antifungal activity against Saccharomyces cerevisiae assessed as inhibition of extracellular acidification measured after 12 mins in presence of glucose | Saccharomyces cerevisiae | 7 | ALA5252545 | organism-based format | Scientific Literature | |
7. | ALA5254151 | Functional | Antifungal activity against Candida albicans assessed as reduction in intracellular ATP levels incubated for 30 mins by BacTiter-Glo luminescent cell viability assay (Rvb = 38+/-17 nM) | Candida albicans | 7 | ALA5252545 | organism-based format | Scientific Literature | |
8. | ALA5254152 | Functional | Antifungal activity against Aspergillus fumigatus ATCC 13073 assessed as inhibition of fungal growth incubated for 24 hrs by CLSI broth microdilution method | Aspergillus fumigatus | 15 | ALA5252545 | organism-based format | Scientific Literature | |
9. | ALA5254153 | Functional | Antifungal activity against Aspergillus flavus ATCC MY A-1005 assessed as inhibition of fungal growth incubated for 24 hrs by CLSI broth microdilution method | Aspergillus flavus | 15 | ALA5252545 | organism-based format | Scientific Literature | |
10. | ALA5254155 | Binding | Inhibition of Saccharomyces cerevisiae H+ ATPase pma1 isoform assessed as reduction in ATP hydrolysis rate at 50 uM measured upto 150 sec by measuring NADP-coupled ATPase activity by spectrophotometry method | Saccharomyces cerevisiae | 1 | ALA5252545 | single protein format | Scientific Literature | |
11. | ALA5254157 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as inhibition of bacterial growth incubated for 16 to 29 hrs | Staphylococcus aureus | 15 | ALA5252545 | organism-based format | Scientific Literature | |
12. | ALA5254158 | Physicochemical | Dissociation constant, pKa of the compound | 5 | ALA5252545 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA5254159 | Binding | Inhibition of Saccharomyces cerevisiae H+ ATPase pma1 isoform assessed as ATP hydrolysis incubated for 30 mins by colorimetric method | Saccharomyces cerevisiae | 19 | ALA5252545 | single protein format | Scientific Literature | |
14. | ALA5254160 | Functional | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 incubated for 24 hrs by CLSI broth microdilution method | Saccharomyces cerevisiae | 19 | ALA5252545 | organism-based format | Scientific Literature | |
15. | ALA5254161 | Functional | Antifungal activity against Candida albicans ATCC SC5314 incubated for 24 hrs by CLSI broth microdilution method | Candida albicans | 19 | ALA5252545 | organism-based format | Scientific Literature | |
16. | ALA5254162 | Binding | Inhibition of Candida albicans H+ ATPase assessed as ATP hydrolysis incubated for 30 mins by colorimetric method | Candida albicans | 15 | ALA5252545 | assay format | Scientific Literature | |
17. | ALA5254163 | Binding | Inhibition of mammalia H+ ATPase assessed as ATP hydrolysis incubated for 30 mins by colorimetric method | Mammalia | 15 | ALA5252545 | assay format | Scientific Literature | |
18. | ALA5254164 | Binding | Inhibition of mammalia NA+/K+ ATPase assessed as ATP hydrolysis incubated for 30 mins by colorimetric method | Mammalia | 15 | ALA5252545 | assay format | Scientific Literature | |
19. | ALA5254165 | Functional | Antifungal activity against Candida krusei ATCC 6258 incubated for 24 hrs by CLSI broth microdilution method | Pichia kudriavzevii | 15 | ALA5252545 | organism-based format | Scientific Literature | |
20. | ALA5254166 | Functional | Antifungal activity against Candida glabrata ATCC 90030 incubated for 24 hrs by CLSI broth microdilution method | Nakaseomyces glabratus | 15 | ALA5252545 | organism-based format | Scientific Literature |