# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4339580 | Binding | Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 measured after 2.5 hrs by fluorescence polarization assay | Homo sapiens | 58 | ALA4339194 | assay format | Scientific Literature | |
2. | ALA4339581 | Binding | Inhibition of C-terminal fluorescein-labeled human cadherin (819 to 873 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 measured after 2.5 hrs by fluorescence polarization assay | Homo sapiens | 2 | ALA4339194 | assay format | Scientific Literature | |
3. | ALA4339582 | Binding | Inhibition of C-terminal fluorescein-labeled human APC-R3 (1477 to 1519 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 measured after 2.5 hrs by fluorescence polarization assay | Homo sapiens | 2 | ALA4339194 | assay format | Scientific Literature | |
4. | ALA4339583 | Binding | Selectivity ratio of Ki for inhibition of C-terminal fluorescein-labeled human cadherin (819 to 873 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 to Ki for Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 | Homo sapiens | 2 | ALA4339194 | assay format | Scientific Literature | |
5. | ALA4339584 | Binding | Selectivity ratio of Ki for inhibition of C-terminal fluorescein-labeled human APC-R3 (1477 to 1519 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 to Ki for Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 | Homo sapiens | 2 | ALA4339194 | assay format | Scientific Literature |