# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA648502 | Functional | Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver | Aves | 1 | ALA1130582 | organism-based format | Scientific Literature | |
2. | ALA648503 | Functional | Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from avian liver | Aves | 1 | ALA1130582 | organism-based format | Scientific Literature | |
3. | ALA648670 | Functional | Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from Bacillus stearothermophilus | Geobacillus stearothermophilus | 1 | ALA1130582 | organism-based format | Scientific Literature | |
4. | ALA648671 | Functional | Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from Bacillus stearothermophilus | Geobacillus stearothermophilus | 1 | ALA1130582 | organism-based format | Scientific Literature | |
5. | ALA823139 | Functional | Effective concentration to activate gammadelta T cells | 40 | ALA1135637 | cell-based format | Scientific Literature | ||
6. | ALA759782 | Functional | Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from porcine liver | Sus scrofa | 1 | ALA1130582 | organism-based format | Scientific Literature | |
7. | ALA759783 | Functional | Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from porcine liver | Sus scrofa | 1 | ALA1130582 | organism-based format | Scientific Literature | |
8. | ALA3380664 | Binding | Inhibition of Populus trichocarpa DXS | Populus sieboldii x Populus grandidentata | 2 | ALA3351771 | assay format | Scientific Literature | |
9. | ALA934225 | Functional | Agonist activity at human Vgamma9Vdelta2 receptor expressed in T cells assessed as stimulation of TNFalpha release by ELISA | Homo sapiens | 12 | ALA1142304 | cell-based format | Scientific Literature | |
10. | ALA1008289 | Functional | Immunostimulatory activity in human Vgamma9/Vdelta2 T cells assessed as TNFalpha production after 12 hrs by ELISA | Homo sapiens | 14 | ALA1136950 | cell-based format | Scientific Literature | |
11. | ALA1008290 | ADME | Stability in presence of alkaline phosphatase | 2 | ALA1136950 | assay format | Scientific Literature | ||
12. | ALA1008291 | ADME | Stability in presence alkaline phosphatase after 20 mins by HPLC-MS analysis | 2 | ALA1136950 | assay format | Scientific Literature | ||
13. | ALA1008292 | ADME | Stability in presence alkaline phosphatase after 30 mins by HPLC-MS analysis | 2 | ALA1136950 | assay format | Scientific Literature | ||
14. | ALA1008293 | ADME | Stability in presence alkaline phosphatase after 60 mins by HPLC-MS analysis | 2 | ALA1136950 | assay format | Scientific Literature | ||
15. | ALA816009 | Functional | Activity against isopentenyl pyrophosphate (IPP) in Vgamma9 / Vdelta2 T cell | Homo sapiens | 5 | ALA1136675 | cell-based format | Scientific Literature | |
16. | ALA816010 | Functional | Effective concentration range of compound was determined in stimulating Vgamma9 / Vdelta2 T cell | Homo sapiens | 8 | ALA1136675 | cell-based format | Scientific Literature | |
17. | ALA816011 | Functional | Mean effective concentration of compound was determined in stimulating Vgamma9 / Vdelta2 T cell | Homo sapiens | 5 | ALA1136675 | cell-based format | Scientific Literature | |
18. | ALA1036733 | Functional | Stimulation of human Vgamma9Vdelta2 T lymphocytes assessed as gamma delta expansion factor after 7 days | Homo sapiens | 9 | ALA1142544 | assay format | Scientific Literature | |
19. | ALA4367522 | Binding | Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated cell proliferation by measuring increase in CD3+ cells preincubated for 3 days followed by 11 days incubation post compound washout and subsequent IL2 stimulation for every 3 days measured after 14 days by flow cytometry | Homo sapiens | 11 | ALA4364297 | cell-based format | Scientific Literature | |
20. | ALA4367529 | Binding | Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated IFNgamma production measured after 48 hrs by ELISA | Homo sapiens | 11 | ALA4364297 | assay format | Scientific Literature |