# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4379008 | Functional | Antiproliferative activity against human SJSA1 cells expressing wild-type p53 incubated for 72 hrs by MTT assay | Homo sapiens | 6 | ALA4376831 | cell-based format | Scientific Literature | |
2. | ALA4379013 | Binding | Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr with TMR-labelled PDI followed by compound addition and measured after 1 hr by fluorescence polarization assay | Homo sapiens | 6 | ALA4376831 | cell-based format | Scientific Literature | |
3. | ALA4379049 | ADME | Cytotoxicity against human HeLa cells incubated for 72 hrs using FAM-labeled compound by MTT assay | Homo sapiens | 4 | ALA4376831 | cell-based format | Scientific Literature | |
4. | ALA4379050 | ADME | Induction of cell membrane disruption in human HeLa cells incubated for 4 hrs using FAM-labeled compound by by LDH assay | Homo sapiens | 4 | ALA4376831 | cell-based format | Scientific Literature |