# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4364841 | Binding | Inhibition of Plasmodium falciparum 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate in presence of beta2 inhibitor WLW-VS | Plasmodium falciparum | 27 | ALA4364250 | assay format | Scientific Literature | |
2. | ALA4364842 | ADME | Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrate | Homo sapiens | 27 | ALA4364250 | single protein format | Scientific Literature | |
3. | ALA4364843 | ADME | Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrate | Homo sapiens | 27 | ALA4364250 | single protein format | Scientific Literature | |
4. | ALA4364844 | Functional | Antimalarial activity against erythrocytic stage of Plasmodium falciparum 3D7 measured after 72 hrs by SYBR green dye based fluorescence assay | Plasmodium falciparum | 27 | ALA4364250 | organism-based format | Scientific Literature | |
5. | ALA4364848 | Binding | Inhibition of MV151 binding to Plasmodium falciparum 20S proteasome beta2 subunit preincubated for 1 hr followed by MV151 addition and measured after 1 hr by fluorescence assay | Plasmodium falciparum | 4 | ALA4364250 | assay format | Scientific Literature | |
6. | ALA4364849 | Binding | Inhibition of MV151 binding to Plasmodium falciparum 20S proteasome beta1 subunit preincubated for 1 hr followed by MV151 addition and measured after 1 hr by fluorescence assay | Plasmodium falciparum | 4 | ALA4364250 | assay format | Scientific Literature |