# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4390897 | Binding | Inhibition of HCV genotype 1a wild-type NS5B RNA dependent RNA polymerase transfected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 3 days by steady-glo luciferase reporter gene assay | Hepatitis C virus subtype 1a | 26 | ALA4390640 | assay format | Scientific Literature | |
2. | ALA4390898 | Binding | Inhibition of HCV genotype 1b wild-type NS5B RNA dependent RNA polymerase infected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 48 hrs by steady-glo luciferase reporter gene assay | Hepatitis C virus subtype 1b | 26 | ALA4390640 | assay format | Scientific Literature | |
3. | ALA4390899 | Binding | Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase C316N mutant infected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 48 hrs by steady-glo luciferase reporter gene assay | Hepatitis C virus subtype 1b | 26 | ALA4390640 | assay format | Scientific Literature | |
4. | ALA4390900 | Binding | Inhibition of HCV genotype 1a NS5B RNA dependent RNA polymerase C316Y mutant transfected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 3 days by steady-glo luciferase reporter gene assay | Hepatitis C virus subtype 1a | 26 | ALA4390640 | assay format | Scientific Literature |