# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4387948 | Binding | Inhibition of recombinant cN-II (unknown origin) assessed as reduction in inorganic phosphate production at 200 uM pre-incubated for 10 mins followed by addition of IMP as substrate and measured after 5 mins by malachite green based assay relative to control | Homo sapiens | 20 | ALA4387703 | single protein format | Scientific Literature | |
2. | ALA4387950 | Binding | Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
3. | ALA4387951 | Binding | Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate assessed as substrate Kcat by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
4. | ALA4387952 | Binding | Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate assessed as substrate Km by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
5. | ALA4387953 | Binding | Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
6. | ALA4387954 | Binding | Noncompetitive inhibition of recombinant cN-II (unknown origin) assessed as substrate Kcat using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
7. | ALA4387955 | Binding | Noncompetitive inhibition of recombinant cN-II (unknown origin) assessed as substrate Km using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
8. | ALA4387956 | Binding | Uncompetitive inhibition of recombinant cN-II (unknown origin) assessed as substrate Kcat using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
9. | ALA4387957 | Binding | Uncompetitive inhibition of recombinant cN-II (unknown origin) assessed as substrate Km using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
10. | ALA4387958 | Binding | Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
11. | ALA4387959 | Binding | Mixed type inhibition of recombinant cN-II (unknown origin) assessed as substrate Kcat using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
12. | ALA4387960 | Binding | Mixed type inhibition of recombinant cN-II (unknown origin) assessed as substrate Km using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
13. | ALA4387961 | Binding | Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
14. | ALA4387962 | Binding | Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for enzyme substrate complex using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analysis | Homo sapiens | 4 | ALA4387703 | single protein format | Scientific Literature | |
15. | ALA4387963 | Functional | Antiproliferative activity against human RL cells assessed as reduction in cell survival incubated for 72 hrs by MTT assay | Homo sapiens | 25 | ALA4387703 | cell-based format | Scientific Literature |