| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4344288 | Binding | Inhibition of recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPH | Homo sapiens | 4 | ALA4342459 | assay format | Scientific Literature | |
| 2. | ALA4676018 | Toxicity | Toxicity in dog | Canis lupus familiaris | 1 | ALA4673244 | assay format | Scientific Literature | |
| 3. | ALA4676019 | Toxicity | Toxicity in rat | Rattus norvegicus | 1 | ALA4673244 | assay format | Scientific Literature | |
| 4. | ALA4676020 | Toxicity | Genotoxicity in human TK6 cells by micronucleus test | Homo sapiens | 1 | ALA4673244 | cell-based format | Scientific Literature | |
| 5. | ALA4676021 | Toxicity | Genotoxicity in Salmonella typhimurium by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA4673244 | assay format | Scientific Literature | |
| 6. | ALA4676022 | Binding | Inhibition of PDE10A1 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 7. | ALA4676023 | Binding | Inhibition of human ERG | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 8. | ALA4676024 | ADME | Induction of CYP3A4 (unknown origin) at 30 uM | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 9. | ALA4676025 | ADME | Induction of CYP2B6 (unknown origin) at 30 uM | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 10. | ALA4676026 | ADME | Induction of CYP1A2 (unknown origin) at 30 uM | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 11. | ALA4676027 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 12. | ALA4676028 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 13. | ALA4676029 | ADME | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 14. | ALA4676030 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 15. | ALA4676031 | ADME | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 16. | ALA4676032 | ADME | Inhibition of CYP2B6 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 17. | ALA4676033 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA4673244 | single protein format | Scientific Literature | |
| 18. | ALA4676034 | Functional | In vivo inhibition of KHK in po dosed Sprague-Dawley rat assessed as reduction in F1P level in liver pretreated for 1 hr followed by fructose infusion for 2 mins measured by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4673244 | organism-based format | Scientific Literature | |
| 19. | ALA4676035 | Functional | In vivo inhibition of KHK in po dosed Sprague-Dawley rat assessed as reduction in F1P level in kidney pretreated for 1 hr followed by fructose infusion for 2 mins measured by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4673244 | organism-based format | Scientific Literature | |
| 20. | ALA4676036 | ADME | Oral bioavailability in Beagle dog at 5 mg/kg using crystalline form of sample by LC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4673244 | organism-based format | Scientific Literature |
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