# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4305804 | Binding | Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus expression system using eIF4E-binding protein 1 peptide and ATP as substrate incubated for 30 mins by LANCE ultra kinase assay | Homo sapiens | 22 | ALA4304763 | assay format | Scientific Literature | |
2. | ALA4305805 | Binding | Inhibition of recombinant human full length N-terminal GST-tagged CDK6 (1 to 326 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus expression system using eIF4E-binding protein 1 peptide and ATP as substrate incubated for 30 mins by LANCE ultra kinase assay | Homo sapiens | 22 | ALA4304763 | assay format | Scientific Literature | |
3. | ALA4305806 | Binding | Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (1 to 298 residues)/cyclin A2 (1 to 432 residues) expressed in baculovirus expression system using eIF4E-binding protein 1 peptide and ATP as substrate incubated for 30 mins by LANCE ultra kinase assay | Homo sapiens | 22 | ALA4304763 | assay format | Scientific Literature | |
4. | ALA4305807 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 4 to 6 days by cell titer-glo luminescent cell viability assay | Homo sapiens | 22 | ALA4304763 | cell-based format | Scientific Literature | |
5. | ALA4305808 | Functional | Antiproliferative activity against human T47D cells assessed as reduction in cell growth incubated for 4 to 6 days by cell titer-glo luminescent cell viability assay | Homo sapiens | 22 | ALA4304763 | cell-based format | Scientific Literature | |
6. | ALA4305809 | Functional | Antiproliferative activity against human ZR-75-1 cells assessed as reduction in cell growth incubated for 4 to 6 days by cell titer-glo luminescent cell viability assay | Homo sapiens | 22 | ALA4304763 | cell-based format | Scientific Literature | |
7. | ALA4305810 | Functional | Antiproliferative activity against human COLO205 cells assessed as reduction in cell growth incubated for 4 to 6 days by cell titer-glo luminescent cell viability assay | Homo sapiens | 22 | ALA4304763 | cell-based format | Scientific Literature | |
8. | ALA4305811 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 4 to 6 days by cell titer-glo luminescent cell viability assay | Homo sapiens | 22 | ALA4304763 | cell-based format | Scientific Literature |