| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4478225 | B | Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate incubated for 10 mins followed by substrate addition by mobility shift assay | Homo sapiens | 36 | ALA4477208 | assay format | Scientific Literature | |
| 2. | ALA4478228 | F | Antiproliferative activity against human MV4-11 cells harboring FLT3-ITD mutant after 72 hrs by MTT assay | Homo sapiens | 38 | ALA4477208 | cell-based format | Scientific Literature | |
| 3. | ALA4478229 | F | Antiproliferative activity against FLT3-deficient human K562 cells after 72 hrs by MTT assay | Homo sapiens | 38 | ALA4477208 | cell-based format | Scientific Literature | |
| 4. | ALA4478230 | A | Antiproliferative activity against human WI38 cells after 72 hrs by SRB assay | Homo sapiens | 38 | ALA4477208 | cell-based format | Scientific Literature | |
| 5. | ALA4478231 | B | Inhibition of FLT3 autophosphorylation in human MV4-11 cells at 10 nM after 2 hrs by Western blot analysis | Homo sapiens | 2 | ALA4477208 | cell-based format | Scientific Literature | |
| 6. | ALA4478232 | B | Inhibition of FLT3 in human MV4-11 cells assessed as downregulation of AKT phosphorylation after 2 hrs by Western blot analysis | Homo sapiens | 2 | ALA4477208 | cell-based format | Scientific Literature | |
| 7. | ALA4478233 | B | Inhibition of FLT3 in human MV4-11 cells assessed as downregulation of ERK1/2 phosphorylation after 2 hrs by Western blot analysis | Homo sapiens | 2 | ALA4477208 | cell-based format | Scientific Literature | |
| 8. | ALA4478234 | B | Inhibition of FLT3 in human MV4-11 cells assessed as downregulation of STAT5 phosphorylation after 2 hrs by Western blot analysis | Homo sapiens | 2 | ALA4477208 | cell-based format | Scientific Literature | |
| 9. | ALA4478235 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G0/G1 phase at 1 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 69.55%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 10. | ALA4478236 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G2 phase at 1 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 13.95%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 11. | ALA4478237 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at S phase at 1 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 16.50%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 12. | ALA4478238 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G0/G1 phase at 10 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 69.55%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 13. | ALA4478239 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G2 phase at 10 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 13.95%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 14. | ALA4478240 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at S phase at 10 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 16.50%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 15. | ALA4478241 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G0/G1 phase at 100 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 69.55%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 16. | ALA4478242 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G2 phase at 100 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 13.95%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 17. | ALA4478243 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at S phase at 100 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 16.50%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 18. | ALA4478244 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G0/G1 phase at 1000 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 69.55%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 19. | ALA4478245 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at G2 phase at 1000 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 13.95%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature | |
| 20. | ALA4478246 | F | Cell cycle arrest in human MV4-11 cells assessed as accumulation at S phase at 1000 nM after 48 hrs by PI/RNase staining based FACS analysis (Rvb = 16.50%) | Homo sapiens | 1 | ALA4477208 | cell-based format | Scientific Literature |
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