| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4479676 | B | Inhibition of full-length recombinant human GST-tagged MARK3 expressed in baculovirus expression system using biotinylated-Cdc25C peptide substrate measured after 2 hrs by HTRF assay | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 2. | ALA4479677 | B | Inhibition of MARK4 in mouse cortical neurons assessed as inhibition of okadaic acid-induced tau phosphorylation at S262 residue preincubated for 15 mins followed okadaic acid challenge for 1.5 hrs by immunostaining method | Mus musculus | 4 | single protein format | Scientific Literature | ||
| 3. | ALA4479678 | A | Clearance in Sprague-Dawley rat at 1 mL/kg, iv administered through catheter measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 4. | ALA4479679 | A | Oral bioavailability in Sprague-Dawley rat at 5 mL/kg administered through gastric gavage measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA4479680 | A | Volume of distribution in Sprague-Dawley rat at 1 mL/kg, iv administered through catheter or 5 mL/kg administered through gastric gavage measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4479681 | A | Substrate activity at human MDR1 expressed in LLC-PK1 cells assessed as efflux ratio of permeability across basolateral to apical over apical to basolateral side at 5 uM | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA4479682 | A | Substrate activity at rat MDR1 expressed in LLC-PK1 cells assessed as efflux ratio of permeability across basolateral to apical over apical to basolateral side at 5 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4479683 | A | Apparent permeability from basolateral to apical side over apical to basolateral side in pig LLC-PK1 cells expressing MDR1 (unknown origin) at 5 uM measured after 3 hrs | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4479684 | P | Solubility of the compound at pH 7 | 15 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA4479689 | B | Inhibition of full-length human His-tagged ABL1 expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 11. | ALA4479690 | B | Inhibition of full-length recombinant human His-tagged ADRBK1 expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 12. | ALA4479691 | B | Inhibition of full-length recombinant human His-tagged AKT1-alpha expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 13. | ALA4479692 | B | Inhibition of full-length recombinant human His-tagged AKT2 expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 14. | ALA4479693 | B | Inhibition of full-length recombinant human His-tagged AKT3 expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 15. | ALA4479694 | B | Inhibition of recombinant human GST-tagged ALK4 catalytic domain expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 16. | ALA4479695 | B | Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 17. | ALA4479696 | B | Inhibition of full-length recombinant human GST and His-tagged AMPK alpha2/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 18. | ALA4479697 | B | Inhibition of full-length recombinant human His-tagged AURKB expressed in baculovirus expression system by LanthaScreen assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 19. | ALA4479698 | B | Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 20. | ALA4479699 | B | Inhibition of full-length recombinant human GST-tagged BRAF expressed in baculovirus expression system by Z'-LYTE assay | Homo sapiens | 4 | assay format | Scientific Literature |
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