# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4402109 | B | Inhibition of His-tagged p97 (unknown origin) in presence of ATP and PNP by UV-transparent microplate assay | Homo sapiens | 19 | ALA4400565 | single protein format | Scientific Literature | |
2. | ALA4402110 | P | GSH reactivity in PBS buffer assessed as half life at 1 uM after presence of GSH by LC-MS/MS analysis | 13 | ALA4400565 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4402111 | F | Antiproliferative activity against human MIAPaCa2 cells | Homo sapiens | 19 | ALA4400565 | cell-based format | Scientific Literature | |
4. | ALA4402118 | B | Inhibition of p97 ATPase activity in human HEK293T cells based Ubv-GFP cells assessed as increase Ub-v-GFP accumulation at 2 uM after 4 hrs by Western blot analysis | Homo sapiens | 14 | ALA4400565 | cell-based format | Scientific Literature | |
5. | ALA4402128 | P | GSH reactivity in PBS buffer assessed as GSH adduct formation at 1 uM after presence of GSH by LC-MS/MS analysis | 13 | ALA4400565 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4402134 | B | Irreversible inhibition of p97 in human A373 cells co-expressing US11 and HA-tagged MCH class 1 heavy chain H2A assessed as half life for MHC class 1 heavy chain degradation at 2 uM incubated for 1 hr followed by further incubation in drug-free medium in presence of cycloheximide by Western blot analysis | Homo sapiens | 2 | ALA4400565 | cell-based format | Scientific Literature |