| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4321056 | F | Antiproliferative activity against human NALM6 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4321057 | F | Antiproliferative activity against mouse leukemia cells overexpressing BCR/ABL after 72 hrs by CellTiter-Glo luminescent cell viability assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4321058 | F | Antiproliferative activity against human KOPN8 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4321059 | F | Antiproliferative activity against human SUP-B15 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4321060 | F | Antiproliferative activity against human UOCB1 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4321061 | A | Antiproliferative activity against human BJ cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4321069 | F | Induction of apoptosis in human NALM6 cells after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4321070 | F | Induction of apoptosis in human KOPN8 cells assessed as late apoptotic cells at 20 uM after 32 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4321071 | F | Cell cycle arrest in human NALM6 cells assessed as accumulation at G0/G1 phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4321072 | F | Cell cycle arrest in human NALM6 cells assessed as accumulation at G2/M phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4321074 | B | Modulation of recombinant wild type GABAA receptor alpha1beta2gamma2S (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GABA-evoked chloride current at 10 uM at -70 mV holding potential by two-microelectrode voltage clamp assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA4321075 | B | Modulation of recombinant wild type GABAA receptor alpha1beta2gamma2S (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GABA-evoked chloride current at 100 uM at -70 mV holding potential by two-microelectrode voltage clamp assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 13. | ALA4321076 | A | Cytotoxicity against mouse J774 cells assessed as reduction in cell viability after 48 hrs by resazurin dye-based fluorometric analysis | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 14. | ALA4321077 | F | Antileishmanial activity against Leishmania amazonensis MHOM/Br/79/Mari promastigotes after 48 hrs by resazurin dye-based fluorometric analysis | Leishmania amazonensis | 10 | organism-based format | Scientific Literature | ||
| 15. | ALA4321078 | F | Antileishmanial activity against Leishmania guyanensis 141/93 promastigotes after 48 hrs by resazurin dye-based fluorometric analysis | Leishmania guyanensis | 10 | organism-based format | Scientific Literature | ||
| 16. | ALA4321079 | F | Antileishmanial activity against Leishmania donovani MHOM/IN/80/DD8 promastigotes after 48 hrs by resazurin dye-based fluorometric analysis | Leishmania donovani | 10 | organism-based format | Scientific Literature | ||
| 17. | ALA4321080 | F | Antileishmanial activity against Leishmania infantum MCAN/ES/96/BCN150 promastigotes after 48 hrs by resazurin dye-based fluorometric analysis | Leishmania infantum | 10 | organism-based format | Scientific Literature | ||
| 18. | ALA4321081 | T | Selectivity index, ratio of CC50 for mouse J774 cells to IC50 for Leishmania amazonensis MHOM/Br/79/Mari promastigotes | 8 | assay format | Scientific Literature | |||
| 19. | ALA4321082 | T | Selectivity index, ratio of CC50 for mouse J774 cells to IC50 for Leishmania guyanensis 141/93 promastigotes | 8 | assay format | Scientific Literature | |||
| 20. | ALA4321083 | T | Selectivity index, ratio of CC50 for mouse J774 cells to IC50 for Leishmania donovani MHOM/IN/80/DD8 promastigotes | 8 | assay format | Scientific Literature |
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