| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4363629 | B | Inhibition of CDYL in C57BL/6 mouse hippocampal neurons as increase in MYT1 mRNA expression at 150 uM incubated for 24 hrs by RT-qPCR analysis | Mus musculus | 1 | ALA4359913 | assay format | Scientific Literature | |
| 2. | ALA4363630 | B | Binding affinity to recombinant human N-terminal GST-tagged CDYL (1 to 60 residues) expressed in Escherichia coli BL2 by SPR analysis | Homo sapiens | 61 | ALA4359913 | assay format | Scientific Literature | |
| 3. | ALA4363633 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as increase in MYT1 mRNA expression incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 3 | ALA4359913 | cell-based format | Scientific Literature | |
| 4. | ALA4363634 | B | Binding affinity to recombinant human N-terminal GST-tagged CDYL2 (1 to 70 residues) expressed in Escherichia coli BL2 by SPR analysis | Homo sapiens | 53 | ALA4359913 | assay format | Scientific Literature | |
| 5. | ALA4363635 | B | Binding affinity to recombinant human N-terminal GST-tagged CDY1 (1 to 65 residues) expressed in Escherichia coli BL2 by SPR analysis | Homo sapiens | 53 | ALA4359913 | assay format | Scientific Literature | |
| 6. | ALA4363636 | B | Binding affinity to recombinant human N-terminal GST-tagged CBX7 (1 to 62 residues) expressed in Escherichia coli BL2 by SPR analysis | Homo sapiens | 53 | ALA4359913 | assay format | Scientific Literature | |
| 7. | ALA4363639 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as increase in BDNF mRNA expression incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 2 | ALA4359913 | cell-based format | Scientific Literature | |
| 8. | ALA4363640 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as increase in VGF mRNA expression incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 2 | ALA4359913 | cell-based format | Scientific Literature | |
| 9. | ALA4363641 | B | Inhibition of CDYL in human HEK293T cells assessed as increase in MYT1 mRNA expression at 50 to 200 uM incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 3 | ALA4359913 | cell-based format | Scientific Literature | |
| 10. | ALA4363642 | B | Inhibition of CDYL in human HEK293T cells assessed as increase in BDNF mRNA expression at 50 to 200 uM incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 3 | ALA4359913 | cell-based format | Scientific Literature | |
| 11. | ALA4363643 | B | Inhibition of CDYL in human HEK293T cells assessed as increase in VGF mRNA expression at 50 to 200 uM incubated for 24 hrs by RT-qPCR analysis | Homo sapiens | 3 | ALA4359913 | cell-based format | Scientific Literature | |
| 12. | ALA4363646 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as decrease in enrichment of CDYL at MYT1 promoter site at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 13. | ALA4363647 | B | Binding affinity to CDYL in human SH-SY5Y cells assessed as increase in protein thermal stability at 150 uM incubated for 10 mins at room temperature followed by exposure to 40 to 67 degC for 4 mins followed by cooling for 3 mins at room temperature by CETSA | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 14. | ALA4363648 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as decrease in enrichment of CDYL at BDNF promoter site at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 15. | ALA4363649 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as decrease in enrichment of CDYL at VGF promoter site at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 16. | ALA4363650 | F | Effect on CDYL recruitment onto HOXA3 promoter site in human SH-SY5Y cells at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 17. | ALA4363651 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as decrease in enrichment of H3K27me3 at MYT1 promoter site at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 18. | ALA4363652 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as decrease in enrichment of H3K27me3 at BDNF promoter site at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 19. | ALA4363653 | B | Inhibition of CDYL in human SH-SY5Y cells assessed as decrease in enrichment of H3K27me3 at VGF promoter site at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature | |
| 20. | ALA4363654 | F | Effect on enrichment of H3K27me3 at HOXA3 promoter site in human SH-SY5Y cells at 150 uM incubated for 24 hrs by ChIP-qPCR analysis | Homo sapiens | 1 | ALA4359913 | cell-based format | Scientific Literature |
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